Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 4/20 | 0.53 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.53 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.53 |
| ▸ | LMNA | P02545 | 1/20 | 0.53 |
| ▸ | GAA | P10253 | 1/20 | 0.53 |
| ▸ | HTT | P42858 | 1/20 | 0.53 |
| ▸ | HRH3 | Q9Y5N1 | 7/20 | 0.51 |
| ▸ | MEN1 | O00255 | 2/20 | 0.49 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.49 |
| ▸ | LTA4H | P09960 | 1/20 | 0.48 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10690170 | 0.91 | KMT2A (0.50) | KMT2AKDM4EALDH1A1LMNAGAA | |
| SCHEMBL10692724 | 0.88 | HRH3 (0.49) | KMT2AKDM4EALDH1A1LMNAGAA | |
| Oxalic Acid SCHEMBL10695599 | 0.86 | KDM4E (0.59) | KMT2AKDM4EALDH1A1LMNAGAA | |
| SCHEMBL10697150 | 0.86 | KDM4E (0.56) | KMT2AKDM4EALDH1A1LMNAGAA | |
| Oxalic Acid SCHEMBL10692238 | 0.81 | KDM4E (0.55) | KMT2AKDM4EALDH1A1LMNAGAA | |
| SCHEMBL10690668 | 0.78 | HRH3 (0.53) | KMT2AKDM4EALDH1A1LMNAGAA | |
| SCHEMBL7415229 | 0.74 | KMT2A (0.61) | KMT2AKDM4EALDH1A1LMNAGAA | |
| SCHEMBL9532091 | 0.74 | HRH3 (0.50) | KMT2AKDM4EALDH1A1LMNAGAA | |
| SCHEMBL10697040 | 0.74 | KDM4E (0.67) | KMT2AKDM4EALDH1A1LMNAGAA | |
| SCHEMBL9834622 | 0.73 | KMT2A (0.58) | KMT2AMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0252876-A1 | Hydrogenated 1-phenoxyalkylpyridine-3-carboxylic-acid compounds | CIBA-GEIGY AG (CH) | 1988-01-13 | — | — | EP | disclosed |