Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 2/20 | 0.64 |
| ▸ | BUB1 | O43683 | 1/20 | 0.42 |
| ▸ | HTR2C | P28335 | 4/20 | 0.40 |
| ▸ | BRD4 | O60885 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 2/20 | 0.39 |
| ▸ | F2 | P00734 | 3/20 | 0.37 |
| ▸ | F10 | P00742 | 1/20 | 0.37 |
| ▸ | PDE7A | Q13946 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6994471 | 0.85 | ALDH1A1 (0.53) | KMT2AHTR2CALDH1A1KDM4EMAPT | |
| SCHEMBL8911487 | 0.74 | KMT2A (0.56) | KMT2ABUB1HTR2CBRD4ALDH1A1 | |
| SCHEMBL15519819 | 0.74 | KMT2A (0.56) | KMT2ABUB1HTR2CBRD4ALDH1A1 | |
| SCHEMBL16886968 | 0.72 | HTR2C (0.39) | KMT2AHTR2CALDH1A1KDM4EMAPT | |
| SCHEMBL15606100 | 0.72 | HTR2C (0.39) | KMT2AHTR2CALDH1A1KDM4EMAPT | |
| SCHEMBL16663984 | 0.71 | HTR2C (0.48) | KMT2AHTR2CALDH1A1MAPT | |
| SCHEMBL7613074 | 0.71 | KMT2A (0.56) | KMT2ABRD4ALDH1A1MAPTPDE7A | |
| SCHEMBL15606018 | 0.71 | HTR2C (0.51) | KMT2AHTR2CALDH1A1KDM4E | |
| SCHEMBL7034883 | 0.71 | KMT2A (0.52) | KMT2ABUB1HTR2CBRD4ALDH1A1 | |
| SCHEMBL30834248 | 0.71 | KMT2A (0.52) | KMT2ABUB1HTR2CBRD4ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0240107-B1 | THIANAPHTHENE DERIVATIVES, THEIR PRODUCTION AND USE | Sankyo Company Limited (JP) | 1991-08-21 | — | — | EP | disclosed |
| US-5021444-A | Anticoagulants | SANKYO COMPANY LIMITED (JP) | 1991-06-04 | — | — | US | disclosed |
| US-4847272-A | ANTICOAGULANTS | SANKYO COMPANY LIMITED (JP) | 1989-07-11 | — | — | US | disclosed |
| EP-0240107-A1 | Thianaphthene derivatives, their production and use | Sankyo Company Limited (JP) | 1987-10-07 | — | — | EP | disclosed |