Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALOX5 | P09917 | 1/20 | 0.94 |
| ▸ | DRD2 | P14416 | 12/20 | 0.72 |
| ▸ | DRD3 | P35462 | 12/20 | 0.72 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.53 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9834884 | 1.00 | ALOX5 (0.94) | ALOX5DRD2DRD3SMN1; SMN2 | |
| Tagorizine SCHEMBL6008778 | 0.97 | ALOX5 (1.00) | ALOX5DRD2DRD3SMN1; SMN2 | |
| Tagorizine SCHEMBL6008781 | 0.97 | ALOX5 (1.00) | ALOX5DRD2DRD3SMN1; SMN2 | |
| Tagorizine SCHEMBL29359054 | 0.97 | ALOX5 (1.00) | ALOX5DRD2DRD3SMN1; SMN2 | |
| Tagorizine SCHEMBL139324 | 0.97 | ALOX5 (1.00) | ALOX5DRD2DRD3SMN1; SMN2 | |
| SCHEMBL10824600 | 0.87 | DRD2 (0.94) | ALOX5DRD2DRD3SMN1; SMN2 | |
| SCHEMBL10824599 | 0.87 | DRD2 (0.94) | ALOX5DRD2DRD3SMN1; SMN2 | |
| Hydrochloric Acid SCHEMBL10826444 | 0.86 | DRD2 (0.92) | ALOX5DRD2DRD3SMN1; SMN2 | |
| Hydrochloric Acid SCHEMBL10826443 | 0.86 | DRD2 (0.92) | ALOX5DRD2DRD3SMN1; SMN2 | |
| SCHEMBL9617895 | 0.86 | ALOX5 (0.80) | ALOX5DRD2DRD3SMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0210782-B1 | PYRIDINE COMPOUNDS, PROCESS FOR THE PREPARATION THEREOF AND PHARMACEUTICAL COMPOSITION CONTAINING THE SAME | Dainippon Pharmaceutical Co., Ltd. (JP) | 1991-04-17 | — | — | EP | disclosed |
| US-4778796-A | ω-(3-pyridyl)alkenamide derivatives and anti-allergenic pharmaceutical compositions containing same | DAINIPPON PHARMACEUTICAL CO., LTD. (JP) | 1988-10-18 | — | — | US | disclosed |
| EP-0210782-A2 | Pyridine compounds, process for the preparation thereof and pharmaceutical composition containing the same | Dainippon Pharmaceutical Co., Ltd. (JP) | 1987-02-04 | — | — | EP | disclosed |