Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PPOX | P50336 | 8/20 | 0.52 |
| ▸ | GAA | P10253 | 1/20 | 0.45 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.44 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.44 |
| ▸ | MAPT | P10636 | 1/20 | 0.44 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.44 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.44 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.44 |
| ▸ | HTT | P42858 | 1/20 | 0.44 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.44 |
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
| ▸ | NR1I2 | O75469 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.41 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.41 |
| ▸ | RORC | P51449 | 1/20 | 0.37 |
| ▸ | P2RX3 | P56373 | 2/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.35 |
| ▸ | POLB | P06746 | 1/20 | 0.35 |
| ▸ | HPGD | P15428 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10573053 | 0.83 | PPOX (0.47) | PPOXGAACYP1A2CYP3A4MAPT | |
| SCHEMBL10573275 | 0.83 | PPOX (0.47) | PPOXGAACYP1A2CYP3A4MAPT | |
| SCHEMBL10573220 | 0.82 | PPOX (0.47) | PPOXGAACYP1A2CYP3A4MAPT | |
| SCHEMBL10578483 | 0.82 | PPOX (0.47) | PPOXGAACYP1A2CYP3A4MAPT | |
| SCHEMBL10883676 | 0.81 | PPOX (0.56) | PPOXGAACYP1A2CYP3A4MAPT | |
| SCHEMBL10530873 | 0.80 | PPOX (0.45) | PPOXGAACYP1A2CYP3A4MAPT | |
| SCHEMBL10575583 | 0.80 | PPOX (0.45) | PPOXGAACYP1A2CYP3A4MAPT | |
| SCHEMBL10578943 | 0.79 | PPOX (0.44) | PPOXGAACYP1A2CYP3A4MAPT | |
| SCHEMBL10530843 | 0.79 | BCAT1 (0.60) | PPOX | |
| SCHEMBL10577441 | 0.79 | PPOX (0.48) | PPOXGAACYP1A2CYP3A4MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0210137-B1 | CONDENSED TRIAZOLO COMPOUNDS | CIBA-GEIGY AG (CH) | 1991-09-11 | — | — | EP | disclosed |
| US-4957535-A | HERBICIDES | CIBA-GEIGY CORPORATION (US) | 1990-09-18 | — | — | US | disclosed |
| US-4789394-A | PREEMERGENCE, POSTEMERGENCE PLANT GROWTH REGULATORS | CIBA-GEIGY CORPORATION (US) | 1988-12-06 | — | — | US | disclosed |
| EP-0210137-A2 | Condensed triazolo compounds | CIBA-GEIGY AG (CH) | 1987-01-28 | — | — | EP | disclosed |