Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 9/20 | 0.42 |
| ▸ | LMNA | P02545 | 2/20 | 0.42 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.42 |
| ▸ | TRPA1 | O75762 | 2/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.34 |
| ▸ | CHRM5 | P08912 | 2/20 | 0.34 |
| ▸ | CHRM1 | P11229 | 2/20 | 0.34 |
| ▸ | CHRM3 | P20309 | 2/20 | 0.34 |
| ▸ | TSHR | P16473 | 2/20 | 0.34 |
| ▸ | PGR | P06401 | 1/20 | 0.34 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.34 |
| ▸ | CHRM4 | P08173 | 1/20 | 0.34 |
| ▸ | HTR1A | P08908 | 1/20 | 0.34 |
| ▸ | CHRNB2 | P17787 | 1/20 | 0.34 |
| ▸ | TBXA2R | P21731 | 1/20 | 0.34 |
| ▸ | CHRNB4 | P30926 | 1/20 | 0.34 |
| ▸ | CHRNA3 | P32297 | 1/20 | 0.34 |
| ▸ | CHRNA7 | P36544 | 1/20 | 0.34 |
| ▸ | CHRNA4 | P43681 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8839818 | 0.85 | ALOX15 (0.41) | TDP1ALDH1A1LMNAHSD17B10SMN1; SMN2 | |
| SCHEMBL888659 | 0.84 | ALDH1A1 (0.50) | TDP1ALDH1A1LMNAHSD17B10SMN1; SMN2 | |
| SCHEMBL5930106 | 0.81 | TDP1 (0.45) | TDP1ALDH1A1LMNAHSD17B10TRPA1 | |
| SCHEMBL4397098 | 0.78 | — | — | |
| SCHEMBL4276311 | 0.78 | — | — | |
| SCHEMBL4390746 | 0.78 | — | — | |
| SCHEMBL4390752 | 0.78 | — | — | |
| SCHEMBL4255246 | 0.78 | TDP1 (0.38) | TDP1ALDH1A1LMNAHSD17B10TRPA1 | |
| SCHEMBL13459987 | 0.77 | TDP1 (0.45) | TDP1ALDH1A1LMNAHSD17B10SMN1; SMN2 | |
| SCHEMBL5358516 | 0.77 | TDP1 (0.45) | TDP1ALDH1A1LMNAHSD17B10SMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0210203-B1 | PROPANOL DERIVATIVES | SYMBICOM AB (SE) | 1991-08-07 | — | — | EP | disclosed |
| US-4933510-A | Propanol derivatives | SYMBICOM AKTIEBOLAG (SE) | 1990-06-12 | — | — | US | disclosed |
| WO-1986004056-A1 | PROPANOL DERIVATIVES | SYN-TEK AB (SE) | 1986-07-17 | — | — | WO | disclosed |