SCHEMBL9835109

SCHEMBL9835109

CC(C)(C)C/C(=C/c1ccc(Cl)cc1)CO

nearest known ligand 0.44

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CYP2C9 P11712 1/20 0.44
TRPA1 O75762 1/20 0.40
HDAC3 O15379 1/20 0.39
HDAC4 P56524 1/20 0.39
HDAC1 Q13547 1/20 0.39
HDAC7 Q8WUI4 1/20 0.39
HDAC2 Q92769 1/20 0.39
HDAC10 Q969S8 1/20 0.39
HDAC11 Q96DB2 1/20 0.39
HDAC8 Q9BY41 1/20 0.39
HDAC6 Q9UBN7 1/20 0.39
HDAC9 Q9UKV0 1/20 0.39
HDAC5 Q9UQL6 1/20 0.39
GRIK1 P39086 1/20 0.36
CYP1A2 P05177 1/20 0.36
PTGS2 P35354 2/20 0.36
FBP1 P09467 1/20 0.36
ALOX5 P09917 1/20 0.36
PTGS1 P23219 1/20 0.36
PPARA Q07869 1/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9835116 1.00 CYP2C9 (0.44) CYP2C9TRPA1HDAC3HDAC4HDAC1
SCHEMBL9870391 1.00 CYP2C9 (0.44) CYP2C9TRPA1HDAC3HDAC4HDAC1
SCHEMBL11830924 0.79 TRPA1 (0.43) CYP2C9TRPA1HDAC3HDAC4HDAC1
SCHEMBL11830929 0.79 TRPA1 (0.43) CYP2C9TRPA1HDAC3HDAC4HDAC1
SCHEMBL9518168 0.74 CYP2C9 (0.46) CYP2C9TRPA1HDAC3HDAC4HDAC1
SCHEMBL9637013 0.74 CYP2C9 (0.46) CYP2C9TRPA1HDAC3HDAC4HDAC1
SCHEMBL9835244 0.74 CYP2C9 (0.46) CYP2C9TRPA1HDAC3HDAC4HDAC1
SCHEMBL9835208 0.73 RAB9A (0.51) MEN1KMT2ARAB9AATM
SCHEMBL9835215 0.73 RAB9A (0.51) MEN1KMT2ARAB9AATM
SCHEMBL9872100 0.73 RAB9A (0.51) MEN1KMT2ARAB9AATM

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0334035-B1 AZOLYL PROPENYL AND AZOLYL METHYLOXIRAN DERIVATIVES, AND FUNGICIDES CONTAINING THEM BASF Aktiengesellschaft (DE) 1991-11-21 EP disclosed
US-5057531-A AZOLYLMETHYLOXIRANES AND FUNGICIDES CONTAINING THESE COMPOUNDS BASF AKTIENGESELLSCHAFT (DE) 1991-10-15 US disclosed
EP-0334035-A1 Azolyl propenyl and azolyl methyloxiran derivatives, and fungicides containing them BASF Aktiengesellschaft (DE) 1989-09-27 EP disclosed