Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ATP4A | P20648 | 8/20 | 0.49 |
| ▸ | ATP4B | P51164 | 8/20 | 0.49 |
| ▸ | CYP2C9 | P11712 | 6/20 | 0.49 |
| ▸ | CYP3A4 | P08684 | 4/20 | 0.49 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.49 |
| ▸ | DDAH1 | O94760 | 2/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.49 |
| ▸ | ABCB1 | P08183 | 2/20 | 0.49 |
| ▸ | MAPT | P10636 | 2/20 | 0.49 |
| ▸ | HPGD | P15428 | 2/20 | 0.49 |
| ▸ | FASN | P49327 | 2/20 | 0.49 |
| ▸ | ABCG2 | Q9UNQ0 | 2/20 | 0.49 |
| ▸ | SLC22A2 | O15244 | 1/20 | 0.49 |
| ▸ | LMNA | P02545 | 1/20 | 0.49 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.49 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.49 |
| ▸ | SLC47A2 | Q86VL8 | 1/20 | 0.49 |
| ▸ | SLC47A1 | Q96FL8 | 1/20 | 0.49 |
| ▸ | RUNX1 | Q01196 | 2/20 | 0.46 |
| ▸ | CBFB | Q13951 | 2/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23988602 | 0.92 | ATP4A (0.41) | ATP4AATP4BCYP2C9CYP3A4KDM4E | |
| SCHEMBL9835200 | 0.92 | ATP4A (0.41) | ATP4AATP4BCYP2C9CYP3A4KDM4E | |
| SCHEMBL12644579 | 0.92 | ATP4A (0.41) | ATP4AATP4BCYP2C9CYP3A4KDM4E | |
| Pantoprazole SCHEMBL29530572 | 0.90 | ATP4A (0.63) | ATP4AATP4BCYP2C9CYP3A4KDM4E | |
| Pantoprazole SCHEMBL29463615 | 0.90 | ATP4A (0.63) | ATP4AATP4BCYP2C9CYP3A4KDM4E | |
| Pantoprazole SCHEMBL29466 | 0.90 | ATP4A (0.63) | ATP4AATP4BCYP2C9CYP3A4KDM4E | |
| Pantoprazole SCHEMBL30777582 | 0.90 | ATP4A (0.63) | ATP4AATP4BCYP2C9CYP3A4KDM4E | |
| Pantoprazole SCHEMBL723548 | 0.90 | ATP4A (0.63) | ATP4AATP4BCYP2C9CYP3A4KDM4E | |
| Pantoprazole SCHEMBL22198 | 0.90 | ATP4A (0.63) | ATP4AATP4BCYP2C9CYP3A4KDM4E | |
| SCHEMBL10712947 | 0.89 | ATP4A (0.49) | ATP4AATP4BCYP2C9CYP3A4KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4738975-A | Pyridine derivatives, and use as anti-ulcer agents | TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) | 1988-04-19 | — | — | US | claimed |
| EP-0208452-B1 | PYRIDINE DERIVATIVES, THEIR PRODUCTION AND USE | Takeda Chemical Industries, Ltd. (JP) | 1991-09-18 | — | — | EP | disclosed |