Pantoprazole

Pantoprazole

SCHEMBL723548

COc1ccnc(C[S+]([O-])c2nc3ccc(OC(F)F)cc3[nH]2)c1OC

nearest known ligand 0.63

Full drug profile on Sugi Atlas →

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ATP4A P20648 15/20 0.63
ATP4B P51164 15/20 0.63
CYP2C9 P11712 3/20 0.63
CYP3A4 P08684 2/20 0.63
KDM4E B2RXH2 1/20 0.63
SLC22A2 O15244 1/20 0.63
DDAH1 O94760 1/20 0.63
ALDH1A1 P00352 1/20 0.63
LMNA P02545 1/20 0.63
ABCB1 P08183 1/20 0.63
MAPT P10636 1/20 0.63
HPGD P15428 1/20 0.63
ALOX15 P16050 1/20 0.63
ADRA1A P35348 1/20 0.63
FASN P49327 1/20 0.63
SLC47A2 Q86VL8 1/20 0.63
SLC47A1 Q96FL8 1/20 0.63
ABCG2 Q9UNQ0 1/20 0.63
ATP1A1 P05023 9/20 0.54
ATP1B1 P05026 9/20 0.54

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Pantoprazole SCHEMBL29463615 1.00 ATP4A (0.63) ATP4AATP4BCYP2C9CYP3A4KDM4E
Pantoprazole SCHEMBL22198 1.00 ATP4A (0.63) ATP4AATP4BCYP2C9CYP3A4KDM4E
Pantoprazole SCHEMBL29530572 1.00 ATP4A (0.63) ATP4AATP4BCYP2C9CYP3A4KDM4E
Pantoprazole SCHEMBL30777582 1.00 ATP4A (0.63) ATP4AATP4BCYP2C9CYP3A4KDM4E
Pantoprazole SCHEMBL29466 1.00 ATP4A (0.63) ATP4AATP4BCYP2C9CYP3A4KDM4E
Pantoprazole SCHEMBL3179782 0.99 ATP4A (0.62) ATP4AATP4BCYP2C9CYP3A4KDM4E
Pantoprazole SCHEMBL289961 0.99 ATP4A (0.62) ATP4AATP4BCYP2C9CYP3A4KDM4E
Pantoprazole SCHEMBL1994486 0.99 ATP4A (0.62) ATP4AATP4BCYP2C9CYP3A4KDM4E
Pantoprazole SCHEMBL1716779 0.99 ATP4A (0.62) ATP4AATP4BCYP2C9CYP3A4KDM4E
Pantoprazole SCHEMBL29001005 0.99 ATP4A (0.62) ATP4AATP4BCYP2C9CYP3A4KDM4E

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 148 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4398908-A2 TREATMENT OF NEUROLOGICAL DISORDERS GMP Biotechnology Limited (CN) 2024-07-17 EP claimed
US-20240216359-A1 TREATMENT OF NEUROLOGICAL DISORDERS GMP BIOTECHNOLOGY LTD (CN) 2024-07-04 US claimed
US-20240093198-A1 TGF-BETA THERAPEUTICS FOR AGE DISEASE GMP BIOTECHNOLOGY LTD (CN) 2024-03-21 US claimed
WO-2023039345-A2 TREATMENT OF NEUROLOGICAL DISORDERS ONCOTELIC, INC. (US) 2023-03-16 WO claimed
EP-2056884-B1 METHOD AND COMPOSITION TO EVALUATE CYTOCHROME P450 2C19 ISOENZYME ACTIVITY USING A BREATH TEST CAMBRIDGE ISOTOPE LAB INC (US) 2016-11-30 EP claimed
CN-105380919-A Pantoprazole sodium enteric-coated tablet and preparation method thereof SHIMAO TIANJIE PHARMACEUTICALS (JIANGSU) CO LTD 2016-03-09 CN claimed
CN-105310999-A Pantoprazole sodium enteric capsule for treating peptic ulcer LI ZHENGMEI 2016-02-10 CN claimed
CN-105193745-A Pantoprazole sodium freeze-drying medicine composition for injection and preparation method thereof KAMP PHARMACEUTICALS CO LTD 2015-12-30 CN claimed
US-20140154190-A1 Skin Lightening Compositions ELC MANAGEMENT, LLC (US) 2014-06-05 US claimed
US-7683177-B2 Process for preparing 2-[(pyridinyl)methyl]sulfinyl-substituted benzimidazoles and novel chlorinated derivatives of pantoprazole TEVA PHARMACEUTICAL INDUSTRIES LTD (IL) 2010-03-23 US claimed
CN-1689568-A Pharmaceutical composition containing cyclodextrin derivatives and proton pump inhibitor of parietal cell YIN XIAOFENG (CN) 2005-11-02 CN claimed
EP-4673144-A1 CANCER THERAPY WITH TGF-BETA-2 AND IRINOTECAN AGENTS GMP Biotechnology Limited (HK) 2026-01-07 EP disclosed
US-20250382619-A1 CANCER THERAPY WITH TGF-BETA-2 AND IRINOTECAN AGENTS GMP BIOTECHNOLOGY LTD (CN) 2025-12-18 US disclosed
US-20250332340-A1 COMPOSITIONS AND METHODS FOR CNS DISEASES GMP BIOTECHNOLOGY LTD (CN) 2025-10-30 US disclosed
EP-4615467-A2 COMPOSITIONS AND METHODS FOR CNS DISEASES GMP Biotechnology Limited (CN) 2025-09-17 EP disclosed
EP-0944617-B1 CRYSTALS OF BENZIMIDAZOLE DERIVATIVES AND THEIR PRODUCTION TAKEDA CHEMICAL INDUSTRIES LTD (JP) 2003-05-14 EP disclosed
CN-1334731-A Novel pharmaceutical formulations ASTRAZENECA AB (SE) 2002-02-06 CN disclosed
US-6002011-A Crystals of benzimidazole derivatives and their production TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) 1999-12-14 US disclosed
EP-0944617-A1 CRYSTALS OF BENZIMIDAZOLE DERIVATIVES AND THEIR PRODUCTION TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) 1999-09-29 EP disclosed
WO-1998021201-A1 CRYSTALS OF BENZIMIDAZOLE DERIVATIVES AND THEIR PRODUCTION TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) 1998-05-22 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20250382619-A1 CANCER THERAPY WITH TGF-BETA-2 AND IRINOTECAN AGENTS FOLR2, TGFB2, TGFBR2 ATP4A 2353/4885ATP4B 896/4885CYP2C9 3107/4885
US-20140154190-A1 Skin Lightening Compositions TYR, MC1R, AHR ATP4A 3964/4885ATP4B 4059/4885CYP2C9 315/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.