Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TRPA1 | O75762 | 1/20 | 0.41 |
| ▸ | LMNA | P02545 | 1/20 | 0.41 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.41 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.41 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.41 |
| ▸ | HTR2B | P41595 | 1/20 | 0.41 |
| ▸ | CASR | P41180 | 1/20 | 0.37 |
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.37 |
| ▸ | TP53 | P04637 | 2/20 | 0.37 |
| ▸ | SRC | P12931 | 1/20 | 0.33 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.32 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.32 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.32 |
| ▸ | CYP2A6 | P11509 | 2/20 | 0.32 |
| ▸ | CACNA2D1 | P54289 | 2/20 | 0.32 |
| ▸ | CACNA1B | Q00975 | 2/20 | 0.32 |
| ▸ | CACNB1 | Q02641 | 2/20 | 0.32 |
| ▸ | RAPGEF4 | Q8WZA2 | 1/20 | 0.31 |
| ▸ | CACNA1G | O43497 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21331651 | 0.81 | TRPA1 (0.42) | TRPA1LMNACHRM1SLC6A2ADRA1A | |
| SCHEMBL11056577 | 0.80 | LMNA (0.62) | TRPA1LMNACHRM1SLC6A2ADRA1A | |
| SCHEMBL27766137 | 0.79 | TRPA1 (0.41) | TRPA1LMNACHRM1SLC6A2ADRA1A | |
| SCHEMBL11062180 | 0.76 | LMNA (0.47) | TRPA1LMNACHRM1SLC6A2ADRA1A | |
| SCHEMBL10357809 | 0.76 | TDP1 (0.34) | TRPA1LMNACHRM1SLC6A2ADRA1A | |
| SCHEMBL1003317 | 0.76 | TRPA1 (0.45) | TRPA1LMNACHRM1SLC6A2ADRA1A | |
| SCHEMBL19122345 | 0.76 | TRPA1 (0.45) | TRPA1LMNACHRM1SLC6A2ADRA1A | |
| SCHEMBL29757164 | 0.75 | TRPA1 (0.60) | TRPA1LMNACHRM1SLC6A2ADRA1A | |
| SCHEMBL6546836 | 0.75 | CASR (0.50) | TRPA1LMNACHRM1SLC6A2ADRA1A | |
| SCHEMBL599102 | 0.75 | TRPA1 (0.60) | TRPA1LMNACHRM1SLC6A2ADRA1A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0222296-B1 | CO-EXTRUDED BIAXIALLY ORIENTED MULTILAYER FILM | HOECHST AKTIENGESELLSCHAFT (DE) | 1991-09-11 | — | — | EP | disclosed |
| EP-0222296-A2 | Co-extruded biaxially oriented multilayer film | HOECHST AKTIENGESELLSCHAFT (DE) | 1987-05-20 | — | — | EP | disclosed |