Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.30 |
| ▸ | MAPT | P10636 | 1/20 | 0.30 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9834798 | 0.83 | IDO1 (0.33) | — | |
| SCHEMBL10568162 | 0.78 | — | — | |
| SCHEMBL5751031 | 0.73 | MEN1 (0.39) | ALDH1A1MAPT | |
| SCHEMBL5740081 | 0.73 | NQO2 (0.49) | ALDH1A1MAPTL3MBTL1 | |
| SCHEMBL5740906 | 0.73 | MAPT (0.35) | ALDH1A1MAPTL3MBTL1 | |
| SCHEMBL5739849 | 0.73 | MAPT (0.44) | ALDH1A1MAPTL3MBTL1 | |
| SCHEMBL5737972 | 0.72 | MAPT (0.55) | ALDH1A1MAPTL3MBTL1 | |
| SCHEMBL9834389 | 0.71 | PGR (0.41) | — | |
| SCHEMBL9835280 | 0.70 | KDM4E (0.30) | — | |
| SCHEMBL5988492 | 0.70 | TP53 (0.43) | ALDH1A1MAPTL3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0214592-B1 | PYRROLOBENZIMIDAZOLES, PROCESS FOR THEIR PREPARATION AND MEDICAMENTS CONTAINING THESE PRODUCTS | Roche Diagnostics GmbH (DE) | 1991-08-14 | — | — | EP | disclosed |
| US-4730003-A | Tricyclic compounds for treating heart and circulatory diseases | BOEHRINGER MANNHEIM GMBH (DE) | 1988-03-08 | — | — | US | disclosed |
| EP-0214592-A2 | Pyrrolobenzimidazoles, process for their preparation and medicaments containing these products | Roche Diagnostics GmbH (DE) | 1987-03-18 | — | — | EP | disclosed |