Predicted protein targets (top 2)
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9835305 | 0.83 | ALDH1A1 (0.30) | — | |
| SCHEMBL9834389 | 0.75 | PGR (0.41) | — | |
| SCHEMBL9834604 | 0.72 | PGR (0.46) | IDO1 | |
| SCHEMBL9834312 | 0.71 | NQO2 (0.32) | — | |
| SCHEMBL9834705 | 0.70 | NQO2 (0.39) | IDO1 | |
| SCHEMBL7093706 | 0.69 | MAPT (0.55) | IDO1TDO2 | |
| SCHEMBL9834194 | 0.69 | — | — | |
| SCHEMBL9834772 | 0.69 | — | — | |
| SCHEMBL9834438 | 0.65 | TDP2 (0.49) | — | |
| SCHEMBL6071732 | 0.65 | ALDH1A1 (0.38) | IDO1TDO2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0214592-B1 | PYRROLOBENZIMIDAZOLES, PROCESS FOR THEIR PREPARATION AND MEDICAMENTS CONTAINING THESE PRODUCTS | Roche Diagnostics GmbH (DE) | 1991-08-14 | — | — | EP | disclosed |
| US-4730003-A | Tricyclic compounds for treating heart and circulatory diseases | BOEHRINGER MANNHEIM GMBH (DE) | 1988-03-08 | — | — | US | disclosed |
| EP-0214592-A2 | Pyrrolobenzimidazoles, process for their preparation and medicaments containing these products | Roche Diagnostics GmbH (DE) | 1987-03-18 | — | — | EP | disclosed |