Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP2C9 | P11712 | 4/20 | 0.46 |
| ▸ | CYP2C19 | P33261 | 3/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.46 |
| ▸ | MEN1 | O00255 | 2/20 | 0.46 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.46 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.45 |
| ▸ | BRD4 | O60885 | 1/20 | 0.45 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.45 |
| ▸ | HDAC7 | Q8WUI4 | 1/20 | 0.45 |
| ▸ | HDAC5 | Q9UQL6 | 1/20 | 0.45 |
| ▸ | TSHR | P16473 | 2/20 | 0.44 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.44 |
| ▸ | GABBR2 | O75899 | 3/20 | 0.44 |
| ▸ | GABBR1 | Q9UBS5 | 3/20 | 0.44 |
| ▸ | LMNA | P02545 | 2/20 | 0.44 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.44 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.44 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.44 |
| ▸ | DRD3 | P35462 | 1/20 | 0.44 |
| ▸ | BLM | P54132 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL11623648 | 0.98 | CYP2C9 (0.44) | CYP2C9CYP2C19KMT2AMEN1CYP2D6 | |
| SCHEMBL11831535 | 0.94 | FFAR1 (0.45) | CYP2C9CYP2C19KMT2AMEN1CYP2D6 | |
| SCHEMBL997295 | 0.88 | SRC (0.42) | CYP2C9CYP2C19KMT2AMEN1CYP2D6 | |
| SCHEMBL9035355 | 0.82 | BRD4 (0.45) | CYP2C9CYP2C19KMT2AMEN1CYP2D6 | |
| SCHEMBL2306107 | 0.80 | BRD4 (0.44) | CYP2C9CYP2C19KMT2AMEN1CYP2D6 | |
| SCHEMBL11218294 | 0.80 | BRD4 (0.44) | CYP2C9CYP2C19KMT2AMEN1CYP2D6 | |
| SCHEMBL991240 | 0.79 | SRC (0.50) | CYP2C9CYP2C19KMT2AMEN1CYP2D6 | |
| SCHEMBL74366 | 0.78 | SRC (0.56) | CYP2C19CYP2D6HDAC4HDAC7HDAC5 | |
| SCHEMBL6204248 | 0.78 | CES2 (0.52) | KMT2AMEN1TSHRALOX15LMNA | |
| SCHEMBL7823663 | 0.77 | ALDH1A1 (0.44) | LMNAPOLBCES2CES1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 13 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-111809195-B | Electrochemical catalytic oxidation coupling synthesis method of alpha-disulfide dicarboxylic acid compound | 北京工商大学 | 2021-12-21 | — | — | CN | disclosed |
| CN-111809195-A | Electrochemical catalytic oxidation coupling synthesis method of alpha-disulfide dicarboxylic acid compound | 北京工商大学 | 2020-10-23 | — | — | CN | disclosed |
| EP-0256687-B1 | THIAZOLIDIN-4-ONE DERIVATIVES AND ACID ADDITION SALTS THEREOF | SUMITOMO PHARMACEUTICALS COMPANY, LIMITED (JP) | 1991-06-12 | — | — | EP | disclosed |
| US-5021435-A | Administering to a patient suffering from an ulcer caused by stress or gastric acid | SUMITOMO PHARMACEUTICALS COMPANY, LIMITED (JP) | 1991-06-04 | — | — | US | disclosed |
| EP-0325496-A1 | 2-Pyridyl thiazolidin-4-one derivatives as anti-ulcer agents | SUMITOMO PHARMACEUTICALS COMPANY, LIMITED (JP) | 1989-07-26 | — | — | EP | disclosed |
| US-4849434-A | PLATELET ACTIVATING FACTOR ANTAGONIST | SUMITOMO PHARMACEUTICALS COMPANY, LIMITED (JP) | 1989-07-18 | — | — | US | disclosed |
| EP-0256687-A1 | Thiazolidin-4-one derivatives and acid addition salts thereof | SUMITOMO PHARMACEUTICALS COMPANY, LIMITED (JP) | 1988-02-24 | — | — | EP | disclosed |
| US-4652660-A | OXIDATION | BAYER AKTIENGESELLSCHAFT (DE) | 1987-03-24 | — | — | US | disclosed |
| US-4555580-A | FROM PHENYLTHIOGLYCOLIC ACIDS | BAYER AKTIENGESELLSCHAFT (DE) | 1985-11-26 | — | — | US | disclosed |
| US-4528286-A | Method of using certain aryl-mercapto-lower-alkanamides as antiseborrheic agents | HENKEL KOMMANDITGESELLSCHAFT (KGAA) (DE) | 1985-07-09 | — | — | US | disclosed |
| US-4346076-A | Bis-tetrazoylmethyl substituted cephalosporin antibiotics | ELI LILLY AND COMPANY (US) | 1982-08-24 | — | — | US | disclosed |
| EP-0048169-A2 | Bis-tetrazoylmethyl substituted cephalosporin antibiotics, their preparation and pharmaceutical formulations containing them | ELI LILLY AND COMPANY (US) | 1982-03-24 | — | — | EP | disclosed |
| US-4260778-A | Process for the preparation of thioindigo compounds | BAYER AKTIENGESELLSCHAFT (DE) | 1981-04-07 | — | — | US | disclosed |