Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TBXAS1 | P24557 | 13/20 | 0.77 |
| ▸ | GAA | P10253 | 2/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.36 |
| ▸ | AHR | P35869 | 1/20 | 0.35 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.35 |
| ▸ | ALPI | P09923 | 1/20 | 0.35 |
| ▸ | ALPG | P10696 | 1/20 | 0.35 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.35 |
| ▸ | PLAA | Q9Y263 | 1/20 | 0.35 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9835676 | 0.89 | TBXAS1 (0.76) | TBXAS1KDM4EAHRNPSR1ALPI | |
| SCHEMBL9837324 | 0.87 | TBXAS1 (1.00) | TBXAS1GAAALDH1A1ALPIALPG | |
| SCHEMBL9835492 | 0.85 | TBXAS1 (0.80) | TBXAS1GAAALDH1A1ALPIALPG | |
| SCHEMBL9835184 | 0.83 | TBXAS1 (0.61) | TBXAS1GAAALDH1A1KDM4EAHR | |
| SCHEMBL9836019 | 0.80 | TBXAS1 (0.72) | TBXAS1GAAALDH1A1ALPIALPG | |
| SCHEMBL9835986 | 0.79 | TBXAS1 (0.46) | TBXAS1KDM4E | |
| SCHEMBL9836524 | 0.77 | TBXAS1 (0.43) | TBXAS1GAAKDM4ETDP1L3MBTL1 | |
| SCHEMBL9836890 | 0.76 | TBXAS1 (1.00) | TBXAS1 | |
| SCHEMBL9834683 | 0.73 | TBXAS1 (0.40) | TBXAS1ALDH1A1 | |
| SCHEMBL9834823 | 0.73 | TBXAS1 (0.40) | TBXAS1GAAALDH1A1KDM4ENPSR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0240107-B1 | THIANAPHTHENE DERIVATIVES, THEIR PRODUCTION AND USE | Sankyo Company Limited (JP) | 1991-08-21 | — | — | EP | disclosed |
| US-5021444-A | Anticoagulants | SANKYO COMPANY LIMITED (JP) | 1991-06-04 | — | — | US | disclosed |
| US-4847272-A | ANTICOAGULANTS | SANKYO COMPANY LIMITED (JP) | 1989-07-11 | — | — | US | disclosed |
| EP-0240107-A1 | Thianaphthene derivatives, their production and use | Sankyo Company Limited (JP) | 1987-10-07 | — | — | EP | disclosed |