Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TBXAS1 | P24557 | 2/20 | 0.40 |
| ▸ | CA12 | O43570 | 9/20 | 0.31 |
| ▸ | CA9 | Q16790 | 9/20 | 0.31 |
| ▸ | CA2 | P00918 | 2/20 | 0.31 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.30 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9835986 | 0.84 | TBXAS1 (0.46) | TBXAS1CA12CA9CA2HSD17B10 | |
| SCHEMBL9836524 | 0.81 | TBXAS1 (0.43) | TBXAS1CA12CA9CA2 | |
| SCHEMBL9834823 | 0.77 | TBXAS1 (0.40) | TBXAS1CA12CA9CA2ALDH1A1 | |
| SCHEMBL10777645 | 0.75 | TBXAS1 (0.39) | TBXAS1CA12CA9CA2ALDH1A1 | |
| SCHEMBL9835519 | 0.73 | TBXAS1 (0.77) | TBXAS1ALDH1A1 | |
| SCHEMBL9834712 | 0.71 | PNMT (0.42) | TBXAS1CA12CA9CA2ALDH1A1 | |
| SCHEMBL10777505 | 0.70 | TBXAS1 (0.40) | TBXAS1ALDH1A1 | |
| SCHEMBL9835676 | 0.70 | TBXAS1 (0.76) | TBXAS1 | |
| SCHEMBL9836663 | 0.70 | KDM4E (0.36) | TBXAS1CA12CA9CA2ALDH1A1 | |
| SCHEMBL9834672 | 0.69 | KDM4E (0.39) | ALDH1A1HSD17B10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0240107-B1 | THIANAPHTHENE DERIVATIVES, THEIR PRODUCTION AND USE | Sankyo Company Limited (JP) | 1991-08-21 | — | — | EP | disclosed |
| US-5021444-A | Anticoagulants | SANKYO COMPANY LIMITED (JP) | 1991-06-04 | — | — | US | disclosed |
| US-4847272-A | ANTICOAGULANTS | SANKYO COMPANY LIMITED (JP) | 1989-07-11 | — | — | US | disclosed |
| EP-0240107-A1 | Thianaphthene derivatives, their production and use | Sankyo Company Limited (JP) | 1987-10-07 | — | — | EP | disclosed |