Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | THRB | P10828 | 1/20 | 0.35 |
| ▸ | TP53 | P04637 | 1/20 | 0.35 |
| ▸ | TSHR | P16473 | 1/20 | 0.35 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.35 |
| ▸ | DPP4 | P27487 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Methylene Chloride SCHEMBL458175 | 1.00 | THRB (0.35) | THRBTP53TSHRTDP1DPP4 | |
| Methylene Chloride SCHEMBL4067496 | 1.00 | THRB (0.35) | THRBTP53TSHRTDP1DPP4 | |
| Methylene Chloride SCHEMBL8850904 | 1.00 | THRB (0.35) | THRBTP53TSHRTDP1DPP4 | |
| Methylene Chloride SCHEMBL1594598 | 1.00 | THRB (0.35) | THRBTP53TSHRTDP1DPP4 | |
| Methylene Chloride SCHEMBL3298712 | 1.00 | — | — | |
| Methylene Chloride SCHEMBL9277901 | 1.00 | THRB (0.35) | THRBTP53TSHRTDP1DPP4 | |
| Methylene Chloride SCHEMBL7574527 | 1.00 | THRB (0.35) | THRBTP53TSHRTDP1DPP4 | |
| Methylene Chloride SCHEMBL6391133 | 1.00 | THRB (0.35) | THRBTP53TSHRTDP1DPP4 | |
| Methylene Chloride SCHEMBL17451199 | 1.00 | THRB (0.35) | THRBTP53TSHRTDP1DPP4 | |
| Methylene Chloride SCHEMBL9275227 | 1.00 | THRB (0.35) | THRBTP53TSHRTDP1DPP4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0217737-B1 | TETRAHYDRO-BETA-CARBOLINES, PROCESS FOR THEIR PREPARATION AND THEIR USE AS MEDICAMENTS | SCHERING AKTIENGESELLSCHAFT (DE) | 1991-08-14 | — | — | EP | disclosed |
| EP-0217737-A2 | Tetrahydro-beta-carbolines, process for their preparation and their use as medicaments | SCHERING AKTIENGESELLSCHAFT (DE) | 1987-04-08 | — | — | EP | disclosed |