Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | THRB | P10828 | 1/20 | 0.35 |
| ▸ | TP53 | P04637 | 1/20 | 0.35 |
| ▸ | TSHR | P16473 | 1/20 | 0.35 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.35 |
| ▸ | DPP4 | P27487 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Methylene Chloride SCHEMBL4067496 | 1.00 | THRB (0.35) | THRBTP53TSHRTDP1DPP4 | |
| Methylene Chloride SCHEMBL8850904 | 1.00 | THRB (0.35) | THRBTP53TSHRTDP1DPP4 | |
| Methylene Chloride SCHEMBL1594598 | 1.00 | THRB (0.35) | THRBTP53TSHRTDP1DPP4 | |
| Methylene Chloride SCHEMBL3298712 | 1.00 | — | — | |
| Methylene Chloride SCHEMBL9277901 | 1.00 | THRB (0.35) | THRBTP53TSHRTDP1DPP4 | |
| Methylene Chloride SCHEMBL7574527 | 1.00 | THRB (0.35) | THRBTP53TSHRTDP1DPP4 | |
| Methylene Chloride SCHEMBL6391133 | 1.00 | THRB (0.35) | THRBTP53TSHRTDP1DPP4 | |
| Methylene Chloride SCHEMBL9835580 | 1.00 | THRB (0.35) | THRBTP53TSHRTDP1DPP4 | |
| Methylene Chloride SCHEMBL17451199 | 1.00 | THRB (0.35) | THRBTP53TSHRTDP1DPP4 | |
| Methylene Chloride SCHEMBL9275227 | 1.00 | THRB (0.35) | THRBTP53TSHRTDP1DPP4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 53 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20240239778-A1 | GRISEOFULVIN COMPOUND AND PHARMACEUTICAL USE THEREOF | DAIICHI SANKYO COMPANY, LIMITED (JP) | 2024-07-18 | — | — | US | disclosed |
| US-20240197923-A1 | IMIDAZOPYRAZINE DERIVATIVES, PROCESS FOR PREPARATION THEREOF, AND THEIR USES AS LUCIFERINS | INSTITUT PASTEUR (FR) | 2024-06-20 | — | — | US | disclosed |
| US-11993593-B2 | Griseofulvin compound and pharmaceutical use thereof | DAIICHI SANKYO COMPANY, LIMITED (JP) | 2024-05-28 | — | — | US | disclosed |
| US-20240150309-A1 | GRISEOFULVIN COMPOUND | DAIICHI SANKYO COMPANY, LIMITED (JP) | 2024-05-09 | — | — | US | disclosed |
| US-11938199-B2 | Imidazopyrazine derivatives, process for preparation thereof, and their uses as luciferins | INSTITUT PASTEUR (FR) | 2024-03-26 | — | — | US | disclosed |
| US-11834427-B2 | Griseofulvin compound | DAIICHI SANKYO COMPANY, LIMITED (JP) | 2023-12-05 | — | — | US | disclosed |
| US-20230136988-A1 | GRISEOFULVIN COMPOUND | DAIICHI SANKYO COMPANY, LIMITED (JP) | 2023-05-04 | — | — | US | disclosed |
| US-20220411416-A1 | GRISEOFULVIN COMPOUND AND PHARMACEUTICAL USE THEREOF | DAIICHI SANKYO COMPANY, LIMITED (JP) | 2022-12-29 | — | — | US | disclosed |
| EP-4032883-A1 | GRISEOFULVIN COMPOUND | Daiichi Sankyo Company, Limited (JP) | 2022-07-27 | — | — | EP | disclosed |
| CN-108779089-B | Griseofulvin compound | 第一三共株式会社 | 2022-04-29 | — | — | CN | disclosed |
| WO-2006100413-A9 | NOVEL COMPOUNDS DERIVED FROM 5-THIOXYLOSE AND THERAPEUTIC USE THEREOF | FOURNIER LAB SA (FR) | 2007-10-18 | — | — | WO | disclosed |
| WO-2006100413-A2 | NOVEL COMPOUNDS DERIVED FROM 5-THIOXYLOSE AND THERAPEUTIC USE THEREOF | LABORATOIRES FOURNIER S.A. (FR) | 2006-09-28 | — | — | WO | disclosed |
| US-6828435-B2 | Three blocking groups are independently removable under 3 different conditions; using new protection schemes and solid phase synthesis, oligonucleotides are obtained in 5' to 3' direction using phosphoamidites and avoiding depurination | HK PHARMACEUTICALS, INC. | 2004-12-07 | — | — | US | disclosed |
| US-20030194741-A1 | COMBINATORIAL PROTECTING GROUP STRATEGY FOR MULTIFUNCTIONAL MOLECULES | CAPROTEC BIOANALYTICS GMBH (DE) | 2003-10-16 | — | — | US | disclosed |
| US-6552056-B2 | Bactericides; fungicides; miticides; nematocides; for agriculture | NIHON BAYER AGROCHEM K.K. (JP) | 2003-04-22 | — | — | US | disclosed |
| US-20030054410-A1 | Combinatorial protecting group strategy for multifunctional molecules | CAPROTEC BIOANALYTICS GMBH (DE) | 2003-03-20 | — | — | US | disclosed |
| US-20030013750-A1 | Isothiazolecarboxamides and their use as microbicides | NIHOM BAYER AGROCHEM K.K. (JP) | 2003-01-16 | — | — | US | disclosed |
| EP-1185519-A1 | ISOTHIAZOLECARBOXAMIDES AND THEIR USE AS MICROBICIDES | NIHON BAYER AGROCHEM K.K. (JP) | 2002-03-13 | — | — | EP | disclosed |
| WO-2001029014-A1 | ISOTHIAZOLE-5-CARBOXYLIC ESTERS AS MICROBICIDES | NIHON BAYER AGROCHEM K.K. (JP) | 2001-04-26 | — | — | WO | disclosed |
| WO-2000073290-A1 | ISOTHIAZOLECARBOXAMIDES AND THEIR USE AS MICROBICIDES | NIHON BAYER AGROCHEM K.K. (JP) | 2000-12-07 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (11 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-11938199-B2 | Imidazopyrazine derivatives, process for preparation thereof, and their uses as luciferins | NISCH, HLCS, CYP3A5 | THRB 3921/4885TP53 3008/4885TSHR 3922/4885 |
| US-11834427-B2 | Griseofulvin compound | PTGS1, CYP11B1, GRIA1 | THRB 3799/4885TP53 3675/4885TSHR 3587/4885 |
| US-20030194741-A1 | COMBINATORIAL PROTECTING GROUP STRATEGY FOR MULTIFUNCTIONAL MOLECULES | ADAR, RNMT, ATIC | THRB 2747/4885TP53 2277/4885TSHR 1687/4885 |
| US-20240239778-A1 | GRISEOFULVIN COMPOUND AND PHARMACEUTICAL USE THEREOF | ACBD3, NR3C1, GRN | THRB 3373/4885TP53 3454/4885TSHR 3242/4885 |
| US-20240150309-A1 | GRISEOFULVIN COMPOUND | PTGS1, CYP11B1, GRIA1 | THRB 3799/4885TP53 3675/4885TSHR 3587/4885 |
| US-20230136988-A1 | GRISEOFULVIN COMPOUND | PTGS1, CYP11B1, GRIA1 | THRB 3799/4885TP53 3675/4885TSHR 3587/4885 |
| US-20240197923-A1 | IMIDAZOPYRAZINE DERIVATIVES, PROCESS FOR PREPARATION THEREOF, AND THEIR USES AS LUCIFERINS | NISCH, HLCS, CYP3A5 | THRB 3921/4885TP53 3008/4885TSHR 3922/4885 |
| US-20030054410-A1 | Combinatorial protecting group strategy for multifunctional molecules | ADAR, RNMT, RRM1 | THRB 2355/4885TP53 2303/4885TSHR 1523/4885 |
| US-11993593-B2 | Griseofulvin compound and pharmaceutical use thereof | ACBD3, GRN, C1S | THRB 3419/4885TP53 3479/4885TSHR 3252/4885 |
| US-20220411416-A1 | GRISEOFULVIN COMPOUND AND PHARMACEUTICAL USE THEREOF | ACBD3, NR3C1, GRN | THRB 3373/4885TP53 3454/4885TSHR 3242/4885 |
| US-20030013750-A1 | Isothiazolecarboxamides and their use as microbicides | MCL1, MSR1, MPO | THRB 3936/4885TP53 1429/4885TSHR 1732/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.