Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTT | P42858 | 1/20 | 0.38 |
| ▸ | MAPT | P10636 | 1/20 | 0.33 |
| ▸ | ABCB1 | P08183 | 1/20 | 0.32 |
| ▸ | MEN1 | O00255 | 1/20 | 0.30 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28647211 | 0.71 | MEN1 (0.38) | HTTMAPTMEN1KMT2A | |
| SCHEMBL5011348 | 0.71 | MEN1 (0.32) | MAPTMEN1KMT2A | |
| SCHEMBL1857214 | 0.71 | MAPT (0.35) | MAPTABCB1MEN1KMT2A | |
| SCHEMBL21826746 | 0.71 | MAPT (0.35) | MAPTABCB1MEN1KMT2A | |
| SCHEMBL28652285 | 0.70 | — | — | |
| SCHEMBL29078204 | 0.70 | MAPT (0.34) | MAPTABCB1MEN1KMT2A | |
| SCHEMBL1618268 | 0.69 | CCNA2 (0.37) | MEN1KMT2A | |
| SCHEMBL7986917 | 0.69 | CCNA2 (0.37) | MEN1KMT2A | |
| SCHEMBL30781006 | 0.69 | MEN1 (0.33) | ABCB1MEN1KMT2A | |
| SCHEMBL10601999 | 0.69 | MET (0.32) | MEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0200377-B1 | HYDROXAMATES | SQUIBB & SONS INC (US) | 1991-10-09 | — | — | EP | disclosed |
| US-4604407-A | Hydroxamates | E. R. SQUIBB & SONS, INC. (US) | 1986-08-05 | — | — | US | disclosed |