SCHEMBL9835722

SCHEMBL9835722

C=C(C)C(OC(=O)Nc1c(Br)cc(Br)cc1Br)C(=O)OC

nearest known ligand 0.32

Predicted protein targets (top 3)

geneUniProtsupporting neighboursconfidence
SMN1; SMN2 Q16637 1/20 0.32
HSD17B10 Q99714 1/20 0.32
ALDH1A1 P00352 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9835199 0.83 NPC1 (0.39) SMN1; SMN2ALDH1A1
SCHEMBL9836146 0.79 GAA (0.44) SMN1; SMN2ALDH1A1
SCHEMBL9835946 0.78 NLRP3 (0.33) SMN1; SMN2ALDH1A1
SCHEMBL9836182 0.78 ALDH1A1 (0.39) SMN1; SMN2ALDH1A1
SCHEMBL9835088 0.77 HTT (0.40) SMN1; SMN2ALDH1A1
SCHEMBL9833989 0.76 RXFP1 (0.41) SMN1; SMN2ALDH1A1
SCHEMBL9867843 0.76 MEN1 (0.41) SMN1; SMN2HSD17B10ALDH1A1
SCHEMBL9835786 0.73 HPGD (0.43) SMN1; SMN2ALDH1A1
SCHEMBL9835147 0.73 EGFR (0.37) SMN1; SMN2ALDH1A1
SCHEMBL9833996 0.72 SMN1; SMN2 (0.45) SMN1; SMN2HSD17B10ALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0241559-B1 OXAZOLIDINEDIONE DERIVATIVES, PROCESS FOR THEIR PREPARATION, AND HERBICIDES CONTAINING THE SAME SAGAMI CHEMICAL RESEARCH CENTER (JP) 1991-10-30 EP disclosed
US-4983751-A Chemical intermediates SAGAMI CHEMICAL RESEARCH CENTER (JP) 1991-01-08 US disclosed
US-4818272-A NONPHYTOTOXICITY FOR CROPS HELICAL STREAMS SAGAMI CHEMICAL RESEARCH CENTER (JP) 1989-04-04 US disclosed
EP-0241559-A1 OXAZOLIDINEDIONE DERIVATIVES, PROCESS FOR THEIR PREPARATION, AND HERBICIDES CONTAINING THE SAME SAGAMI CHEMICAL RESEARCH CENTER (JP) 1987-10-21 EP disclosed