SCHEMBL9835856

SCHEMBL9835856

CCCS(=O)(=O)Nc1ccc([C]=O)cc1

nearest known ligand 0.49

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
PGR P06401 1/20 0.49
HPGD P15428 5/20 0.46
LMNA P02545 3/20 0.46
HTT P42858 1/20 0.46
SMN1; SMN2 Q16637 1/20 0.46
PTPN5 P54829 1/20 0.45
AR P10275 2/20 0.44
KDR P35968 2/20 0.44
AURKB Q96GD4 2/20 0.44
PLK4 O00444 1/20 0.44
DCLK1 O15075 1/20 0.44
DAPK3 O43293 1/20 0.44
DYRK3 O43781 1/20 0.44
JAK2 O60674 1/20 0.44
ROCK2 O75116 1/20 0.44
PRKD3 O94806 1/20 0.44
MAP4K4 O95819 1/20 0.44
CDK1 P06493 1/20 0.44
ROS1 P08922 1/20 0.44
PRKACA P17612 1/20 0.44

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL3063963 0.88 THRA (0.52) PGRHPGDLMNAHTTSMN1; SMN2
SCHEMBL3059775 0.87 HPGD (0.60) PGRHPGDLMNAHTTSMN1; SMN2
SCHEMBL10586659 0.80 BRD4 (0.47) PGRSMN1; SMN2PTPN5KDRAURKB
SCHEMBL10191923 0.79 CA1 (0.53) PGRHPGDLMNAHTTSMN1; SMN2
SCHEMBL3061130 0.79 NR3C2 (0.42) PGRHPGDLMNAHTTSMN1; SMN2
SCHEMBL7761720 0.78 HPGD (0.58) PGRHPGDLMNAHTTSMN1; SMN2
SCHEMBL4766928 0.78 CA1 (0.52) PGRHPGDLMNAHTTSMN1; SMN2
SCHEMBL7758939 0.78 HPGD (0.48) PGRHPGDLMNAHTTSMN1; SMN2
SCHEMBL21024552 0.78 KMT2A (0.54) PGRHPGDLMNAHTTSMN1; SMN2
SCHEMBL3070153 0.77 HPGD (0.41) PGRHPGDLMNAHTTSMN1; SMN2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0215124-B1 SILVER HALIDE PHOTOGRAPHIC PHOTO-SENSITIVE MATERIAL FUJI PHOTO FILM CO., LTD. (JP) 1991-09-04 EP disclosed
US-4925782-A Silver halide photographic light-sensitive element containing water soluble dye compounds FUJI PHOTO FILM CO., LTD. (JP) 1990-05-15 US disclosed
US-4879204-A HIGH CONTRAST FUJI PHOTO FILM CO., LTD. (JP) 1989-11-07 US disclosed
EP-0319999-A2 Silver halide photographic materials Fuji Photo Film Co., Ltd. (JP) 1989-06-14 EP disclosed
US-4764455-A Color image-forming process FUJI PHOTO FILM CO., LTD. (JP) 1988-08-16 US disclosed
EP-0215124-A1 SILVER HALIDE PHOTOGRAPHIC PHOTO-SENSITIVE MATERIAL FUJI PHOTO FILM CO., LTD. (JP) 1987-03-25 EP disclosed