Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR3A | P46098 | 1/20 | 0.33 |
| ▸ | HTR6 | P50406 | 1/20 | 0.32 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.30 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5459912 | 0.76 | — | — | |
| SCHEMBL5694541 | 0.74 | CHRM2 (0.31) | CHRM2CHRM3 | |
| SCHEMBL708989 | 0.74 | CHRM2 (0.31) | HTR3ACHRM2CHRM3 | |
| SCHEMBL13771787 | 0.74 | MAPT (0.39) | CHRM2CHRM3 | |
| SCHEMBL1414718 | 0.74 | MAPT (0.33) | CHRM2CHRM3 | |
| SCHEMBL3861432 | 0.73 | CHRM2 (0.31) | CHRM2CHRM3 | |
| Ammonia Solution, Strong SCHEMBL27874578 | 0.73 | CHRM2 (0.31) | HTR3ACHRM2CHRM3 | |
| SCHEMBL28247416 | 0.73 | HTR6 (0.32) | HTR6 | |
| SCHEMBL3366367 | 0.73 | CHRM2 (0.31) | CHRM2CHRM3 | |
| Pyrrolidine SCHEMBL27776132 | 0.72 | CHRM2 (0.34) | HTR3ACHRM2CHRM3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0296048-B1 | DERIVATIVES OF PIPERAZINYL ALKYL PIPERAZINE DIONE, PROCESSES FOR THEIR PREPARATION AND PHARMACEUTICAL COMPOSITIONS CONTAINING THEM | ADIR ET COMPAGNIE (FR) | 1991-11-21 | — | — | EP | disclosed |
| EP-0296048-B1 | DERIVATIVES OF PIPERAZINYL ALKYL PIPERAZINE DIONE, PROCESSES FOR THEIR PREPARATION AND PHARMACEUTICAL COMPOSITIONS CONTAINING THEM | ADIR ET COMPAGNIE (FR) | 1991-11-21 | — | — | EP | disclosed |
| EP-0296048-A1 | Derivatives of piperazinyl alkyl piperazine dione, processes for their preparation and pharmaceutical compositions containing them | ADIR ET COMPAGNIE (FR) | 1988-12-21 | — | — | EP | disclosed |
| EP-0296048-A1 | Derivatives of piperazinyl alkyl piperazine dione, processes for their preparation and pharmaceutical compositions containing them | ADIR ET COMPAGNIE (FR) | 1988-12-21 | — | — | EP | disclosed |