Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP3A4 | P08684 | 10/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.37 |
| ▸ | LMNA | P02545 | 3/20 | 0.36 |
| ▸ | PKM | P14618 | 1/20 | 0.36 |
| ▸ | THRB | P10828 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.36 |
| ▸ | CYP2C9 | P11712 | 6/20 | 0.35 |
| ▸ | CYP2C19 | P33261 | 6/20 | 0.35 |
| ▸ | CYP1A2 | P05177 | 4/20 | 0.35 |
| ▸ | CYP2D6 | P10635 | 4/20 | 0.35 |
| ▸ | MEN1 | O00255 | 1/20 | 0.35 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.35 |
| ▸ | TSHR | P16473 | 1/20 | 0.35 |
| ▸ | IDO1 | P14902 | 1/20 | 0.35 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.34 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.34 |
| ▸ | CYP11B1 | P15538 | 1/20 | 0.34 |
| ▸ | CYP11B2 | P19099 | 1/20 | 0.34 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.34 |
| ▸ | CYP51A1 | Q16850 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9835891 | 0.90 | CYP3A4 (0.36) | CYP3A4ALDH1A1LMNATHRBKMT2A | |
| SCHEMBL9836134 | 0.86 | CYP3A4 (0.39) | CYP3A4ALDH1A1LMNAPKMTHRB | |
| SCHEMBL9835425 | 0.84 | CYP3A4 (0.41) | CYP3A4ALDH1A1LMNAPKMTHRB | |
| SCHEMBL9835759 | 0.83 | CYP3A4 (0.35) | CYP3A4ALDH1A1LMNATHRBKMT2A | |
| SCHEMBL9836120 | 0.83 | CYP3A4 (0.37) | CYP3A4ALDH1A1LMNAPKMTHRB | |
| SCHEMBL9835078 | 0.79 | CYP3A4 (0.41) | CYP3A4ALDH1A1LMNAPKMTHRB | |
| SCHEMBL10364012 | 0.78 | CYP3A4 (0.41) | CYP3A4ALDH1A1LMNAPKMTHRB | |
| SCHEMBL15770528 | 0.78 | CYP3A4 (0.39) | CYP3A4ALDH1A1LMNATHRBKMT2A | |
| SCHEMBL9835295 | 0.78 | CYP3A4 (0.42) | CYP3A4ALDH1A1LMNAPKMTHRB | |
| SCHEMBL9833447 | 0.77 | TSHR (0.37) | CYP3A4ALDH1A1LMNAKMT2ACYP2C9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0126430-B1 | PROCESS FOR THE PREPARATION OF 1-TRIAZOLYLETHYLETHER-DERIVATIVES, AND MICROBICIDAL COMPOSITIONS CONTAINING NOVEL 1-TRIAZOLYL-PHENOXYPHENYLETHYLETHER-DERIVATIVES AS ACTIVE INGREDIENTS AND THEIR USE | CIBA-GEIGY AG (CH) | 1991-08-28 | — | — | EP | disclosed |
| US-4945100-A | Process for the preparation of 1-triazolylethyl ether derivatives | CIBA-GEIGY CORPORATION (US) | 1990-07-31 | — | — | US | disclosed |
| EP-0126430-A2 | Process for the preparation of 1-triazolylethylether-derivatives, and microbicidal compositions containing novel 1-triazolyl-phenoxyphenylethylether-derivatives as active ingredients and their use | CIBA-GEIGY AG (CH) | 1984-11-28 | — | — | EP | disclosed |