Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 4/20 | 0.44 |
| ▸ | MEN1 | O00255 | 3/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.44 |
| ▸ | CA12 | O43570 | 2/20 | 0.40 |
| ▸ | CA1 | P00915 | 2/20 | 0.40 |
| ▸ | CA2 | P00918 | 2/20 | 0.40 |
| ▸ | CA9 | Q16790 | 2/20 | 0.40 |
| ▸ | PRSS1 | P07477 | 3/20 | 0.38 |
| ▸ | F2 | P00734 | 2/20 | 0.38 |
| ▸ | KLKB1 | P03952 | 2/20 | 0.38 |
| ▸ | PLG | P00747 | 1/20 | 0.38 |
| ▸ | PLAU | P00749 | 1/20 | 0.38 |
| ▸ | PLAT | P00750 | 1/20 | 0.38 |
| ▸ | ENPP3 | O14638 | 1/20 | 0.38 |
| ▸ | ENPP1 | P22413 | 1/20 | 0.38 |
| ▸ | ENPP2 | Q13822 | 1/20 | 0.38 |
| ▸ | TRPV1 | Q8NER1 | 1/20 | 0.38 |
| ▸ | ACR | P10323 | 1/20 | 0.38 |
| ▸ | FTO | Q9C0B1 | 1/20 | 0.37 |
| ▸ | MAPT | P10636 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Acetic Acid SCHEMBL7314947 | 0.97 | KMT2A (0.45) | KMT2AMEN1SMN1; SMN2CA12CA1 | |
| SCHEMBL7319785 | 0.89 | KMT2A (0.46) | KMT2AMEN1SMN1; SMN2CA12CA1 | |
| SCHEMBL7319794 | 0.86 | KMT2A (0.50) | KMT2AMEN1SMN1; SMN2PRSS1F2 | |
| SCHEMBL7340814 | 0.85 | KMT2A (0.44) | KMT2AMEN1SMN1; SMN2CA12CA1 | |
| SCHEMBL7319782 | 0.82 | KMT2A (0.46) | KMT2AMEN1SMN1; SMN2PRSS1F2 | |
| SCHEMBL9584464 | 0.81 | ALDH1A1 (0.45) | KMT2AMEN1SMN1; SMN2CA12CA1 | |
| SCHEMBL9835061 | 0.80 | KMT2A (0.48) | KMT2AMEN1SMN1; SMN2PRSS1F2 | |
| SCHEMBL9690496 | 0.80 | KMT2A (0.42) | KMT2AMEN1SMN1; SMN2PRSS1F2 | |
| SCHEMBL9690520 | 0.79 | KMT2A (0.45) | KMT2AMEN1SMN1; SMN2PRSS1F2 | |
| SCHEMBL9689310 | 0.79 | PPARG (0.50) | KMT2AMEN1SMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0222608-B1 | DERIVATIVES OF P-GUANIDINOBENZOIC ACID AND PHARMACEUTICAL AGENTS CONTAINING THEM AS ACTIVE INGREDIENT | ONO PHARMACEUTICAL CO., LTD. (JP) | 1991-09-11 | — | — | EP | claimed |
| EP-0222608-A2 | Derivatives of p-guanidinobenzoic acid and pharmaceutical agents containing them as active ingredient | ONO PHARMACEUTICAL CO., LTD. (JP) | 1987-05-20 | — | — | EP | claimed |