Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.60 |
| ▸ | POLB | P06746 | 1/20 | 0.60 |
| ▸ | TBXA2R | P21731 | 1/20 | 0.59 |
| ▸ | TBXAS1 | P24557 | 1/20 | 0.59 |
| ▸ | SGMS1 | Q86VZ5 | 3/20 | 0.56 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.54 |
| ▸ | PKM | P14618 | 1/20 | 0.51 |
| ▸ | MMP3 | P08254 | 1/20 | 0.51 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.50 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.50 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.50 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.50 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.50 |
| ▸ | GAA | P10253 | 2/20 | 0.49 |
| ▸ | KCNA5 | P22460 | 1/20 | 0.49 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.49 |
| ▸ | MAPT | P10636 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9834437 | 0.89 | TBXA2R (0.64) | ALDH1A1TBXA2RTBXAS1SGMS1SMN1; SMN2 | |
| SCHEMBL9836262 | 0.88 | TBXA2R (0.55) | ALDH1A1TBXA2RTBXAS1TDP1MAPT | |
| SCHEMBL9836406 | 0.86 | TBXA2R (0.55) | ALDH1A1TBXA2RTBXAS1SGMS1TDP1 | |
| SCHEMBL10773828 | 0.86 | GAA (0.62) | ALDH1A1POLBSGMS1SMN1; SMN2PKM | |
| SCHEMBL11348800 | 0.81 | TBXA2R (0.79) | ALDH1A1POLBTBXA2RTBXAS1SGMS1 | |
| SCHEMBL21550423 | 0.76 | GAA (0.52) | ALDH1A1POLBSMN1; SMN2PKMTDP1 | |
| SCHEMBL7109149 | 0.76 | ALDH1A1 (1.00) | ALDH1A1POLBSGMS1SMN1; SMN2PKM | |
| SCHEMBL30822632 | 0.75 | CA12 (0.63) | ALDH1A1POLBSMN1; SMN2KDM4ECYP3A4 | |
| SCHEMBL3535994 | 0.75 | CA12 (0.63) | ALDH1A1POLBSMN1; SMN2KDM4ECYP3A4 | |
| SCHEMBL1022817 | 0.75 | ALDH1A1 (0.62) | ALDH1A1POLBSMN1; SMN2GAAMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0239907-B1 | PHENOXYALKANECARBOXYLIC-ACID DERIVATIVES, PROCESS FOR THEIR PREPARATION AND MEDICINES CONTAINING THESE COMPOUNDS | Roche Diagnostics GmbH (DE) | 1991-09-18 | — | — | EP | disclosed |