Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA12 | O43570 | 1/20 | 0.63 |
| ▸ | CA1 | P00915 | 1/20 | 0.63 |
| ▸ | CA2 | P00918 | 1/20 | 0.63 |
| ▸ | CA5A | P35218 | 1/20 | 0.63 |
| ▸ | CA9 | Q16790 | 1/20 | 0.63 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.63 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.60 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.58 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.58 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.58 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.58 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.58 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.58 |
| ▸ | HPGD | P15428 | 1/20 | 0.58 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.58 |
| ▸ | MEN1 | O00255 | 3/20 | 0.57 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.57 |
| ▸ | GAA | P10253 | 2/20 | 0.55 |
| ▸ | HTT | P42858 | 2/20 | 0.55 |
| ▸ | LMNA | P02545 | 1/20 | 0.55 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30822632 | 1.00 | CA12 (0.63) | CA12CA1CA2CA5ACA9 | |
| SCHEMBL10774143 | 0.86 | ALDH1A1 (0.55) | CA12CA1CA2CA5ACA9 | |
| SCHEMBL4616128 | 0.86 | SFRP1 (0.61) | CA12CA1CA2CA5ACA9 | |
| SCHEMBL1022817 | 0.83 | ALDH1A1 (0.62) | CA12CA1CA2CA5ACA9 | |
| SCHEMBL29260186 | 0.82 | MEN1 (0.72) | CA12CA2CA9ALDH1A1CYP1A2 | |
| SCHEMBL9836262 | 0.82 | TBXA2R (0.55) | ALDH1A1MEN1KMT2A | |
| SCHEMBL21550403 | 0.81 | L3MBTL1 (0.63) | CA12CA1CA2CA5ACA9 | |
| SCHEMBL31277189 | 0.81 | L3MBTL1 (0.63) | CA12CA1CA2CA5ACA9 | |
| SCHEMBL23451385 | 0.80 | ALDH1A1 (0.60) | CA12CA2CA9ALDH1A1HSD17B10 | |
| SCHEMBL3535555 | 0.80 | ALDH1A1 (0.60) | CA12CA2CA9ALDH1A1CYP1A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 13 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20210171456-A1 | NOVEL SULFONAMIDE DERIVATIVES HAVING SELECTIVE NOX INHIBITING ACTIVITY | GLUCOX BIOTECH AB (SE) | 2021-06-10 | — | — | US | claimed |
| EP-3790858-A1 | NOVEL SULFONAMIDE DERIVATIVES HAVING SELECTIVE NOX INHIBITING ACTIVITY | Glucox Biotech AB (SE) | 2021-03-17 | — | — | EP | claimed |
| WO-2019215291-A1 | NOVEL SULFONAMIDE DERIVATIVES HAVING SELECTIVE NOX INHIBITING ACTIVITY | GLUCOX BIOTECH AB (SE) | 2019-11-14 | — | — | WO | claimed |
| US-20250136545-A1 | NOVEL SULFONAMIDE DERIVATIVES HAVING SELECTIVE NOX INHIBITING ACTIVITY | GLUCOX BIOTECH AB (SE) | 2025-05-01 | — | — | US | disclosed |
| US-12202790-B2 | Sulfonamide derivatives having selective Nox inhibiting activity | GLUCOX BIOTECH AB (SE) | 2025-01-21 | — | — | US | disclosed |
| CN-117924125-A | Method for preparing sulfonamide derivative through visible light catalysis without metal participation | 苏州大学 | 2024-04-26 | — | — | CN | disclosed |
| US-20210171456-A1 | NOVEL SULFONAMIDE DERIVATIVES HAVING SELECTIVE NOX INHIBITING ACTIVITY | GLUCOX BIOTECH AB (SE) | 2021-06-10 | — | — | US | disclosed |
| EP-3790858-A1 | NOVEL SULFONAMIDE DERIVATIVES HAVING SELECTIVE NOX INHIBITING ACTIVITY | Glucox Biotech AB (SE) | 2021-03-17 | — | — | EP | disclosed |
| WO-2019215291-A1 | NOVEL SULFONAMIDE DERIVATIVES HAVING SELECTIVE NOX INHIBITING ACTIVITY | GLUCOX BIOTECH AB (SE) | 2019-11-14 | — | — | WO | disclosed |
| US-7858619-B2 | Substituted tetrahydroisochinolines as MMP inhibitors, related production method and use as medicine | SANOFI-AVENTIS (FR) | 2010-12-28 | — | — | US | disclosed |
| US-20080090821-A1 | SUBSTITUTED TETRAHYDROISOCHINOLINES AS MMP INHIBITORS, RELATED PRODUCTION METHOD AND USE AS MEDICINE | SANOFI-AVENTIS (FR) | 2008-04-17 | — | — | US | disclosed |
| EP-1869001-A1 | SUBSTITUTED TETRAHYDROISOCHINOLINES AS MMP INHIBITORS, RELATED PRODUCTION METHOD AND USE AS MEDICINE | Sanofi-Aventis (FR) | 2007-12-26 | — | — | EP | disclosed |
| WO-2006102998-A1 | SUBSTITUTED TETRAHYDROISOCHINOLINES AS MMP INHIBITORS, RELATED PRODUCTION METHOD AND USE AS MEDICINE | SANOFI-AVENTIS (DE) | 2006-10-05 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-12202790-B2 | Sulfonamide derivatives having selective Nox inhibiting activity | NOX4, NOX1, NOX5 | CA12 3389/4885CA1 3125/4885CA2 656/4885 |
| US-20210171456-A1 | NOVEL SULFONAMIDE DERIVATIVES HAVING SELECTIVE NOX INHIBITING ACTIVITY | NOX4, NOX1, NOX5 | CA12 3484/4885CA1 3231/4885CA2 615/4885 |
| US-20250136545-A1 | NOVEL SULFONAMIDE DERIVATIVES HAVING SELECTIVE NOX INHIBITING ACTIVITY | NOX4, NOX1, NOX5 | CA12 3484/4885CA1 3231/4885CA2 615/4885 |
| US-20080090821-A1 | SUBSTITUTED TETRAHYDROISOCHINOLINES AS MMP INHIBITORS, RELATED PRODUCTION METHOD AND USE AS MEDICINE | MMP9, MMP3, MMP2 | CA12 2118/4885CA1 1120/4885CA2 573/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.