Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 1.00 |
| ▸ | NPC1 | O15118 | 7/20 | 0.79 |
| ▸ | POLB | P06746 | 1/20 | 0.77 |
| ▸ | RAB9A | P51151 | 6/20 | 0.76 |
| ▸ | MEN1 | O00255 | 3/20 | 0.73 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.73 |
| ▸ | HTT | P42858 | 1/20 | 0.73 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.72 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.71 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.71 |
| ▸ | CA12 | O43570 | 1/20 | 0.70 |
| ▸ | CA1 | P00915 | 1/20 | 0.70 |
| ▸ | CA2 | P00918 | 1/20 | 0.70 |
| ▸ | CA9 | Q16790 | 1/20 | 0.70 |
| ▸ | TP53 | P04637 | 1/20 | 0.68 |
| ▸ | HPGD | P15428 | 1/20 | 0.68 |
| ▸ | ROCK2 | O75116 | 1/20 | 0.64 |
| ▸ | SAE1 | Q9UBE0 | 1/20 | 0.63 |
| ▸ | UBA2 | Q9UBT2 | 1/20 | 0.63 |
| ▸ | NAMPT | P43490 | 2/20 | 0.63 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17916794 | 0.94 | SMN1; SMN2 (0.88) | SMN1; SMN2NPC1POLBRAB9AMEN1 | |
| SCHEMBL23728203 | 0.88 | SMN1; SMN2 (0.79) | SMN1; SMN2NPC1POLBRAB9AMEN1 | |
| SCHEMBL23747473 | 0.88 | SMN1; SMN2 (0.79) | SMN1; SMN2NPC1POLBRAB9AMEN1 | |
| SCHEMBL30361459 | 0.87 | SMN1; SMN2 (0.78) | SMN1; SMN2NPC1POLBRAB9AMEN1 | |
| Hydrochloric Acid SCHEMBL26100400 | 0.87 | SMN1; SMN2 (0.77) | SMN1; SMN2NPC1POLBRAB9AMEN1 | |
| SCHEMBL23728118 | 0.87 | SMN1; SMN2 (0.77) | SMN1; SMN2NPC1POLBRAB9AMEN1 | |
| SCHEMBL16562239 | 0.87 | SMN1; SMN2 (0.77) | SMN1; SMN2NPC1POLBRAB9AMEN1 | |
| SCHEMBL8175404 | 0.87 | RAB9A (0.89) | SMN1; SMN2NPC1POLBRAB9AMEN1 | |
| SCHEMBL5427744 | 0.87 | NPC1 (1.00) | SMN1; SMN2NPC1POLBRAB9AMEN1 | |
| SCHEMBL23747428 | 0.86 | SMN1; SMN2 (0.75) | SMN1; SMN2NPC1POLBRAB9AMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| JP-3167166-A | — | — | None | — | — | JP | disclosed |
| JP-H03167166-A | BENZYLUREA DERIVATIVE AND AGENT FOR REDUCING PHYTOTOXICITY | HOKKO CHEM IND CO LTD | 1991-07-19 | — | — | JP | disclosed |