Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TBXAS1 | P24557 | 4/20 | 0.59 |
| ▸ | TSHR | P16473 | 1/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.43 |
| ▸ | CYP17A1 | P05093 | 1/20 | 0.38 |
| ▸ | CYP11B1 | P15538 | 1/20 | 0.37 |
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.36 |
| ▸ | GAA | P10253 | 2/20 | 0.35 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
| ▸ | CTSA | P10619 | 1/20 | 0.33 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.33 |
| ▸ | MKNK1 | Q9BUB5 | 1/20 | 0.33 |
| ▸ | MKNK2 | Q9HBH9 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
| ▸ | APP | P05067 | 1/20 | 0.33 |
| ▸ | HCAR3 | P49019 | 1/20 | 0.33 |
| ▸ | HCAR2 | Q8TDS4 | 1/20 | 0.33 |
| ▸ | CFTR | P13569 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9835661 | 0.87 | TBXAS1 (0.46) | TBXAS1TSHRSMN1; SMN2CYP17A1CYP11B1 | |
| SCHEMBL9837224 | 0.82 | TBXAS1 (0.43) | TBXAS1TSHRSMN1; SMN2CYP17A1CYP11B1 | |
| SCHEMBL9836166 | 0.74 | TBXAS1 (1.00) | TBXAS1CYP17A1CYP11B1MEN1KMT2A | |
| SCHEMBL9837543 | 0.70 | TSHR (0.40) | TSHRSMN1; SMN2CYP11B1LMNAL3MBTL1 | |
| SCHEMBL7246231 | 0.68 | TSHR (0.67) | TSHRSMN1; SMN2CYP17A1CYP11B1LMNA | |
| SCHEMBL9834753 | 0.68 | TBXAS1 (0.45) | TBXAS1 | |
| SCHEMBL24620828 | 0.65 | SMN1; SMN2 (0.54) | TSHRSMN1; SMN2CYP17A1LMNAL3MBTL1 | |
| SCHEMBL4166356 | 0.64 | KDM4C (0.38) | TBXAS1CYP11B1L3MBTL1GAAMEN1 | |
| SCHEMBL1242879 | 0.64 | SMN1; SMN2 (0.87) | TSHRSMN1; SMN2CYP17A1CYP11B1LMNA | |
| SCHEMBL24621250 | 0.64 | TSHR (0.56) | TSHRSMN1; SMN2CYP17A1CYP11B1LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0240107-B1 | THIANAPHTHENE DERIVATIVES, THEIR PRODUCTION AND USE | Sankyo Company Limited (JP) | 1991-08-21 | — | — | EP | disclosed |