Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TBXAS1 | P24557 | 3/20 | 0.45 |
| ▸ | HIF1A | Q16665 | 2/20 | 0.33 |
| ▸ | DHODH | Q02127 | 1/20 | 0.32 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.30 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9836560 | 0.85 | DHODH (0.34) | TBXAS1HIF1ADHODH | |
| SCHEMBL9835558 | 0.77 | TBXAS1 (0.63) | TBXAS1 | |
| SCHEMBL9836736 | 0.69 | TBXAS1 (0.43) | TBXAS1HIF1ADHODH | |
| SCHEMBL9836236 | 0.68 | TBXAS1 (0.59) | TBXAS1 | |
| SCHEMBL9871950 | 0.64 | NPC1 (0.42) | TBXAS1DHODH | |
| SCHEMBL9871091 | 0.62 | TBXAS1 (0.36) | TBXAS1 | |
| SCHEMBL9837432 | 0.61 | TBXAS1 (0.36) | TBXAS1 | |
| SCHEMBL9834643 | 0.60 | NPC1 (0.38) | — | |
| SCHEMBL5210765 | 0.59 | ACMSD (0.49) | HIF1ADHODHCYP2C9 | |
| SCHEMBL718693 | 0.59 | HSD17B2 (0.46) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0240107-B1 | THIANAPHTHENE DERIVATIVES, THEIR PRODUCTION AND USE | Sankyo Company Limited (JP) | 1991-08-21 | — | — | EP | disclosed |