Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TBXAS1 | P24557 | 12/20 | 0.78 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.38 |
| ▸ | GAA | P10253 | 1/20 | 0.38 |
| ▸ | CYP19A1 | P11511 | 2/20 | 0.38 |
| ▸ | PDE4B | Q07343 | 1/20 | 0.36 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.36 |
| ▸ | AGTR2 | P50052 | 1/20 | 0.36 |
| ▸ | NPC1 | O15118 | 1/20 | 0.35 |
| ▸ | POLB | P06746 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9834133 | 0.92 | TBXAS1 (0.78) | TBXAS1ALDH1A1GAACYP19A1PDE4B | |
| SCHEMBL9834596 | 0.88 | TBXAS1 (1.00) | TBXAS1ALDH1A1GAA | |
| Hydrochloric Acid SCHEMBL9836537 | 0.87 | TBXAS1 (0.98) | TBXAS1ALDH1A1GAA | |
| SCHEMBL9835790 | 0.81 | TBXAS1 (0.79) | TBXAS1ALDH1A1GAAPDE4BPDE4D | |
| SCHEMBL9835990 | 0.81 | TBXAS1 (0.72) | TBXAS1ALDH1A1GAAAGTR2 | |
| SCHEMBL9837142 | 0.79 | TBXAS1 (1.00) | TBXAS1ALDH1A1GAA | |
| Hydrochloric Acid SCHEMBL9836713 | 0.78 | TBXAS1 (0.98) | TBXAS1ALDH1A1GAA | |
| SCHEMBL9837500 | 0.77 | TBXAS1 (0.80) | TBXAS1ALDH1A1GAACYP19A1 | |
| SCHEMBL9871295 | 0.75 | TBXAS1 (0.55) | TBXAS1ALDH1A1GAACYP19A1PDE4B | |
| SCHEMBL9836741 | 0.75 | TBXAS1 (0.53) | TBXAS1ALDH1A1GAACYP19A1NPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0240107-B1 | THIANAPHTHENE DERIVATIVES, THEIR PRODUCTION AND USE | Sankyo Company Limited (JP) | 1991-08-21 | — | — | EP | disclosed |
| US-5021444-A | Anticoagulants | SANKYO COMPANY LIMITED (JP) | 1991-06-04 | — | — | US | disclosed |
| US-4847272-A | ANTICOAGULANTS | SANKYO COMPANY LIMITED (JP) | 1989-07-11 | — | — | US | disclosed |
| EP-0240107-A1 | Thianaphthene derivatives, their production and use | Sankyo Company Limited (JP) | 1987-10-07 | — | — | EP | disclosed |