Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TBXAS1 | P24557 | 15/20 | 0.53 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.37 |
| ▸ | GAA | P10253 | 1/20 | 0.37 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.34 |
| ▸ | NPC1 | O15118 | 1/20 | 0.34 |
| ▸ | POLB | P06746 | 1/20 | 0.34 |
| ▸ | F2 | P00734 | 1/20 | 0.34 |
| ▸ | F10 | P00742 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9835464 | 0.93 | TBXAS1 (0.53) | TBXAS1ALDH1A1GAACYP19A1NPC1 | |
| SCHEMBL9837280 | 0.84 | TBXAS1 (0.36) | TBXAS1ALDH1A1GAAPOLB | |
| SCHEMBL9837100 | 0.80 | TBXAS1 (0.60) | TBXAS1ALDH1A1GAA | |
| SCHEMBL9834134 | 0.79 | POLB (0.34) | ALDH1A1POLB | |
| SCHEMBL9836336 | 0.75 | TBXAS1 (0.78) | TBXAS1ALDH1A1GAACYP19A1NPC1 | |
| SCHEMBL9834133 | 0.73 | TBXAS1 (0.78) | TBXAS1ALDH1A1GAACYP19A1NPC1 | |
| SCHEMBL9835676 | 0.72 | TBXAS1 (0.76) | TBXAS1CYP19A1 | |
| SCHEMBL9836779 | 0.69 | TBXAS1 (0.76) | TBXAS1CYP19A1NPC1POLB | |
| SCHEMBL9834596 | 0.69 | TBXAS1 (1.00) | TBXAS1ALDH1A1GAA | |
| SCHEMBL10772896 | 0.69 | HTT (0.34) | ALDH1A1POLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0240107-B1 | THIANAPHTHENE DERIVATIVES, THEIR PRODUCTION AND USE | Sankyo Company Limited (JP) | 1991-08-21 | — | — | EP | disclosed |
| US-5021444-A | Anticoagulants | SANKYO COMPANY LIMITED (JP) | 1991-06-04 | — | — | US | disclosed |
| US-4847272-A | ANTICOAGULANTS | SANKYO COMPANY LIMITED (JP) | 1989-07-11 | — | — | US | disclosed |