Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTT | P42858 | 3/20 | 0.48 |
| ▸ | PKM | P14618 | 1/20 | 0.48 |
| ▸ | MAPT | P10636 | 10/20 | 0.47 |
| ▸ | MAPK1 | P28482 | 6/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.47 |
| ▸ | GAA | P10253 | 3/20 | 0.47 |
| ▸ | LMNA | P02545 | 2/20 | 0.47 |
| ▸ | TDP1 | Q9NUW8 | 6/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.46 |
| ▸ | L3MBTL1 | Q9Y468 | 4/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.43 |
| ▸ | GLA | P06280 | 1/20 | 0.42 |
| ▸ | ATM | Q13315 | 1/20 | 0.42 |
| ▸ | POLB | P06746 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9836972 | 0.88 | MAPT (0.50) | HTTPKMMAPTMAPK1ALDH1A1 | |
| SCHEMBL9835831 | 0.85 | SMN1; SMN2 (0.57) | HTTPKMMAPTMAPK1ALDH1A1 | |
| SCHEMBL9836886 | 0.85 | ALDH1A1 (0.45) | HTTPKMMAPTMAPK1ALDH1A1 | |
| SCHEMBL9836565 | 0.85 | MAPT (0.49) | HTTPKMMAPTMAPK1ALDH1A1 | |
| SCHEMBL9834545 | 0.85 | ALDH1A1 (0.48) | HTTMAPTMAPK1ALDH1A1SMN1; SMN2 | |
| SCHEMBL9835388 | 0.82 | KMT2A (0.48) | HTTMAPTMAPK1ALDH1A1GAA | |
| SCHEMBL9833790 | 0.81 | SMN1; SMN2 (0.56) | HTTPKMMAPTMAPK1ALDH1A1 | |
| SCHEMBL9837321 | 0.80 | LMNA (0.41) | HTTPKMMAPTMAPK1ALDH1A1 | |
| SCHEMBL9836414 | 0.77 | KMT2A (0.50) | MAPTMAPK1ALDH1A1LMNATDP1 | |
| SCHEMBL11316531 | 0.76 | ALDH1A1 (0.54) | HTTPKMMAPTMAPK1ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0241559-B1 | OXAZOLIDINEDIONE DERIVATIVES, PROCESS FOR THEIR PREPARATION, AND HERBICIDES CONTAINING THE SAME | SAGAMI CHEMICAL RESEARCH CENTER (JP) | 1991-10-30 | — | — | EP | disclosed |
| US-4983751-A | Chemical intermediates | SAGAMI CHEMICAL RESEARCH CENTER (JP) | 1991-01-08 | — | — | US | disclosed |
| US-4818272-A | NONPHYTOTOXICITY FOR CROPS HELICAL STREAMS | SAGAMI CHEMICAL RESEARCH CENTER (JP) | 1989-04-04 | — | — | US | disclosed |