Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 1/20 | 0.45 |
| ▸ | QDPR | P09417 | 2/20 | 0.41 |
| ▸ | HTR6 | P50406 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9838389 | 0.78 | MAPT (0.47) | MAPT | |
| SCHEMBL9838055 | 0.76 | MAPT (0.46) | MAPT | |
| SCHEMBL14733305 | 0.74 | QDPR (0.44) | QDPRHTR6 | |
| SCHEMBL16041291 | 0.74 | QDPR (0.41) | QDPRHTR6 | |
| SCHEMBL9838179 | 0.73 | MAPT (0.43) | MAPT | |
| SCHEMBL31536273 | 0.72 | QDPR (0.45) | QDPRHTR6 | |
| SCHEMBL31718158 | 0.71 | QDPR (0.63) | QDPR | |
| SCHEMBL15134651 | 0.70 | QDPR (0.42) | QDPR | |
| SCHEMBL7077303 | 0.68 | QDPR (0.44) | QDPRHTR6 | |
| SCHEMBL28503673 | 0.67 | HTR6 (0.56) | QDPRHTR6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0104522-B1 | NEW PYRAZOLO(3,4-B)PYRIDINE DERIVATIVES AND PROCESS FOR PRODUCING THEM | GRUPPO LEPETIT S.p.A. (IT) | 1991-05-29 | — | — | EP | disclosed |
| US-4612318-A | CNS-depressant and analgesic tricyclo-[pyrazolo-[3,4-6]-pyridine] derivatives and pharmaceutical compositions thereof | GRUPPO LEPETIT S.P.A. (IT) | 1986-09-16 | — | — | US | disclosed |
| EP-0104522-A2 | New pyrazolo(3,4-b)pyridine derivatives and process for producing them | GRUPPO LEPETIT S.p.A. (IT) | 1984-04-04 | — | — | EP | disclosed |