Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.37 |
| ▸ | TDP1 | Q9NUW8 | 4/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.37 |
| ▸ | HTT | P42858 | 2/20 | 0.37 |
| ▸ | NCOA1 | Q15788 | 2/20 | 0.37 |
| ▸ | NCOA3 | Q9Y6Q9 | 2/20 | 0.37 |
| ▸ | MAPT | P10636 | 2/20 | 0.37 |
| ▸ | HPGD | P15428 | 2/20 | 0.37 |
| ▸ | PPARG | P37231 | 1/20 | 0.37 |
| ▸ | NCOA2 | Q15596 | 1/20 | 0.37 |
| ▸ | PIN1 | Q13526 | 8/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
| ▸ | POLB | P06746 | 1/20 | 0.33 |
| ▸ | GPR35 | Q9HC97 | 1/20 | 0.33 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.32 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.32 |
| ▸ | TSHR | P16473 | 1/20 | 0.32 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.32 |
| ▸ | TXNRD1 | Q16881 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9837792 | 0.80 | CDK2 (0.37) | ALDH1A1TDP1KDM4EHTTNCOA1 | |
| SCHEMBL29381779 | 0.75 | POLB (0.51) | ALDH1A1TDP1KDM4EHTTNCOA1 | |
| SCHEMBL202663 | 0.75 | POLB (0.51) | ALDH1A1TDP1KDM4EHTTNCOA1 | |
| SCHEMBL31197366 | 0.73 | POLB (0.50) | ALDH1A1TDP1KDM4EHTTNCOA1 | |
| Ammonia Solution, Strong SCHEMBL27736895 | 0.73 | POLB (0.50) | ALDH1A1TDP1KDM4EHTTNCOA1 | |
| Hydrochloric Acid SCHEMBL3867195 | 0.73 | POLB (0.50) | ALDH1A1TDP1KDM4EHTTNCOA1 | |
| SCHEMBL2250758 | 0.72 | TSHR (0.47) | ALDH1A1MAPTPOLBCYP3A4TSHR | |
| SCHEMBL10264896 | 0.72 | EGFR (0.44) | ALDH1A1TDP1KDM4EHTTNCOA1 | |
| SCHEMBL405386 | 0.72 | TSHR (0.47) | MAPTMEN1KMT2APOLBTSHR | |
| SCHEMBL29828560 | 0.72 | CHUK (0.48) | ALDH1A1TDP1KDM4EHTTMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0223420-B1 | CONDENSED IMIDAZOPYRIDINE DERIVATIVES | SHIONOGI & CO., LTD. (JP) | 1991-02-27 | — | — | EP | disclosed |
| US-4753951-A | ANTIDEPRESSANTS, ANXIOLYTICS | SHIONOGI & CO., LTD. (JP) | 1988-06-28 | — | — | US | disclosed |
| EP-0223420-A1 | Condensed imidazopyridine derivatives | SHIONOGI & CO., LTD. (JP) | 1987-05-27 | — | — | EP | disclosed |