Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CDK2 | P24941 | 1/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.37 |
| ▸ | MAPT | P10636 | 5/20 | 0.37 |
| ▸ | HTT | P42858 | 3/20 | 0.37 |
| ▸ | HPGD | P15428 | 2/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.37 |
| ▸ | NCOA1 | Q15788 | 2/20 | 0.37 |
| ▸ | NCOA3 | Q9Y6Q9 | 2/20 | 0.37 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.37 |
| ▸ | PPARG | P37231 | 1/20 | 0.37 |
| ▸ | NCOA2 | Q15596 | 1/20 | 0.37 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.36 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.35 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
| ▸ | RAB9A | P51151 | 1/20 | 0.33 |
| ▸ | POLB | P06746 | 1/20 | 0.33 |
| ▸ | EGFR | P00533 | 2/20 | 0.32 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.32 |
| ▸ | GAA | P10253 | 1/20 | 0.32 |
| ▸ | CTSB | P07858 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9836384 | 0.80 | ALDH1A1 (0.37) | ALDH1A1MAPTHTTHPGDKDM4E | |
| SCHEMBL202880 | 0.75 | POLB (0.51) | ALDH1A1MAPTHTTHPGDKDM4E | |
| SCHEMBL18658901 | 0.70 | NR4A2 (0.45) | MAPT | |
| SCHEMBL20319134 | 0.70 | CTSB (0.42) | ALDH1A1MAPTHTTTDP1CYP3A4 | |
| SCHEMBL26620010 | 0.70 | PTGES (0.49) | ALDH1A1MAPTCYP3A4LMNAEGFR | |
| SCHEMBL12182655 | 0.70 | PARP1 (0.40) | CDK2ALDH1A1MAPTNCOA1NCOA3 | |
| SCHEMBL9837779 | 0.69 | ALDH1A1 (0.45) | CDK2ALDH1A1MAPTHTTHPGD | |
| SCHEMBL9838214 | 0.69 | DYRK1A (0.42) | CDK2ALDH1A1MAPTHTTHPGD | |
| SCHEMBL11666956 | 0.69 | CDK2 (0.43) | CDK2ALDH1A1MAPTHPGDTDP1 | |
| SCHEMBL18658922 | 0.67 | ALDH1A1 (0.47) | ALDH1A1MAPTHPGDKDM4ETDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0223420-B1 | CONDENSED IMIDAZOPYRIDINE DERIVATIVES | SHIONOGI & CO., LTD. (JP) | 1991-02-27 | — | — | EP | disclosed |
| US-4753951-A | ANTIDEPRESSANTS, ANXIOLYTICS | SHIONOGI & CO., LTD. (JP) | 1988-06-28 | — | — | US | disclosed |
| EP-0223420-A1 | Condensed imidazopyridine derivatives | SHIONOGI & CO., LTD. (JP) | 1987-05-27 | — | — | EP | disclosed |