Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 7/20 | 0.45 |
| ▸ | HPGD | P15428 | 6/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.45 |
| ▸ | MAPT | P10636 | 3/20 | 0.45 |
| ▸ | GAA | P10253 | 3/20 | 0.45 |
| ▸ | GLA | P06280 | 2/20 | 0.45 |
| ▸ | MEN1 | O00255 | 1/20 | 0.45 |
| ▸ | LMNA | P02545 | 1/20 | 0.45 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.45 |
| ▸ | HTT | P42858 | 1/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.45 |
| ▸ | NPC1 | O15118 | 6/20 | 0.45 |
| ▸ | RAB9A | P51151 | 5/20 | 0.45 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.45 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.45 |
| ▸ | PKM | P14618 | 1/20 | 0.44 |
| ▸ | TP53 | P04637 | 2/20 | 0.43 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.43 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.40 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6420845 | 0.77 | ALDH1A1 (0.65) | KDM4EHPGDALDH1A1MAPTGAA | |
| SCHEMBL10771438 | 0.74 | KDM4E (0.44) | KDM4EHPGDALDH1A1MAPTGAA | |
| SCHEMBL10771178 | 0.68 | TNKS (0.58) | KDM4EHPGDALDH1A1MAPTMEN1 | |
| SCHEMBL28184296 | 0.66 | PDGFRB (0.58) | KDM4EHPGDALDH1A1MAPTGAA | |
| SCHEMBL31305431 | 0.66 | SMPD3 (0.46) | KDM4EHPGDALDH1A1MAPTGAA | |
| SCHEMBL14060083 | 0.66 | SMPD3 (0.46) | KDM4EHPGDALDH1A1MAPTGAA | |
| SCHEMBL18042289 | 0.65 | KDM4E (0.52) | KDM4EHPGDALDH1A1MAPTGAA | |
| SCHEMBL914097 | 0.65 | ALDH1A1 (0.81) | KDM4EHPGDALDH1A1MAPTGAA | |
| SCHEMBL8068757 | 0.64 | GBA1 (0.47) | KDM4EHPGDALDH1A1MAPTGAA | |
| SCHEMBL1147594 | 0.64 | KDM4E (0.65) | KDM4EHPGDALDH1A1MAPTGAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0223420-B1 | CONDENSED IMIDAZOPYRIDINE DERIVATIVES | SHIONOGI & CO., LTD. (JP) | 1991-02-27 | — | — | EP | claimed |
| US-4753951-A | ANTIDEPRESSANTS, ANXIOLYTICS | SHIONOGI & CO., LTD. (JP) | 1988-06-28 | — | — | US | claimed |
| EP-0223420-A1 | Condensed imidazopyridine derivatives | SHIONOGI & CO., LTD. (JP) | 1987-05-27 | — | — | EP | claimed |