Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP1A1 | P04798 | 4/20 | 0.57 |
| ▸ | CYP1B1 | Q16678 | 4/20 | 0.57 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.57 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.57 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.57 |
| ▸ | MAPT | P10636 | 2/20 | 0.57 |
| ▸ | HPGD | P15428 | 2/20 | 0.57 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.57 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.57 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.57 |
| ▸ | TSHR | P16473 | 1/20 | 0.57 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.57 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.57 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.55 |
| ▸ | MAOA | P21397 | 12/20 | 0.55 |
| ▸ | GLA | P06280 | 1/20 | 0.55 |
| ▸ | PGAM1 | P18669 | 1/20 | 0.55 |
| ▸ | CASP1 | P29466 | 1/20 | 0.55 |
| ▸ | CASP7 | P55210 | 1/20 | 0.55 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.55 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12764548 | 0.77 | MAOA (0.61) | CYP1A1CYP1B1KDM4EALDH1A1CYP3A4 | |
| SCHEMBL30674066 | 0.77 | MAOA (0.67) | KDM4EALDH1A1CYP3A4MAPTHPGD | |
| SCHEMBL12608738 | 0.77 | MAOA (0.67) | KDM4EALDH1A1CYP3A4MAPTHPGD | |
| SCHEMBL7228147 | 0.74 | MAOA (0.67) | CYP1B1KDM4EALDH1A1CYP3A4MAPT | |
| Xanthone SCHEMBL41161 | 0.73 | MAOA (1.00) | KDM4EALDH1A1CYP3A4MAPTHPGD | |
| Xanthone SCHEMBL29358061 | 0.73 | MAOA (1.00) | KDM4EALDH1A1CYP3A4MAPTHPGD | |
| Xanthone SCHEMBL29398266 | 0.73 | MAOA (1.00) | KDM4EALDH1A1CYP3A4MAPTHPGD | |
| Xanthone SCHEMBL2354794 | 0.73 | MAOA (1.00) | KDM4EALDH1A1CYP3A4MAPTHPGD | |
| SCHEMBL12608741 | 0.73 | MAOA (0.68) | KDM4EALDH1A1CYP3A4MAPTHPGD | |
| Karanjonol SCHEMBL21828762 | 0.73 | KDM4E (0.71) | CYP1A1CYP1B1KDM4EALDH1A1CYP3A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0175376-B1 | XANTHONE DERIVATIVES AND PROCESS FOR PRODUCING THE SAME | Chugai Seiyaku Kabushiki Kaisha (JP) | 1991-04-03 | — | — | EP | disclosed |
| US-4816479-A | HYPOTENSIVE AGENTS, DIURETICS | CHUGAI SEIYAKU KABUSHIKI KAISHA (JP) | 1989-03-28 | — | — | US | disclosed |
| US-4661607-A | ANTIEDEMIC AGENTS, HYPOTENSIVE AGENTS | CHUGAI SEIYAKU KABUSHIKI KAISHA (JP) | 1987-04-28 | — | — | US | disclosed |
| EP-0175376-A2 | Xanthone derivatives and process for producing the same | Chugai Seiyaku Kabushiki Kaisha (JP) | 1986-03-26 | — | — | EP | disclosed |