Known targets — ChEMBL curated mechanism
ADRA2AADRA2BADRA2CADRB2AGTR1AVPR1AAVPR1BAVPR2BDKRB2CALCRCHRNA3CHRNB4ESR1ESR2GHSRGNRHRGSC1HSPA8MALT1MC1RMC4RNOS1NOS2NOS3OPRK1OXTRRAMP1RAMP2RAMP3SCN5ASSTR1SSTR2SSTR3SSTR4SSTR5dacAdacBdacCfolPftsImrcAmrcBmrdArplArplBrplCrplDrplErplFrplJrplKrplLrplMrplNrplOrplPrplQrplRrplSrplTrplUrplVrplWrplXrplYrpmArpmBrpmCrpmDrpmErpmFrpmGrpmHrpmIrpmJrpsArpsBrpsCrpsDrpsErpsFrpsGrpsHrpsIrpsJrpsKrpsLrpsMrpsNrpsOrpsPrpsQrpsRrpsSrpsTrpsUykgMykgO
The experimentally established mechanism targets of Trifluoroacetic Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA1 | P00915 | 2/20 | 0.56 |
| ▸ | CA4 | P22748 | 4/20 | 0.42 |
| ▸ | FFAR3 | O14843 | 1/20 | 0.35 |
| ▸ | LCK | P06239 | 1/20 | 0.35 |
| ▸ | FYN | P06241 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.35 |
| ▸ | TSHR | P16473 | 2/20 | 0.35 |
| ▸ | CASP1 | P29466 | 1/20 | 0.33 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.33 |
| ▸ | FAHD1 | Q6P587 | 1/20 | 0.33 |
| ▸ | THRB | P10828 | 1/20 | 0.32 |
| ▸ | CA2 | P00918 | 1/20 | 0.30 |
| ▸ | TP53 | P04637 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Trifluoroacetic Acid SCHEMBL28874768 | 0.94 | CA1 (0.50) | CA1CA4FFAR3LCKFYN | |
| Trifluoroacetic Acid SCHEMBL28138602 | 0.94 | CA1 (0.50) | CA1CA4FFAR3LCKFYN | |
| Trifluoroacetic Acid SCHEMBL9752761 | 0.94 | CA1 (0.50) | CA1CA4FFAR3LCKFYN | |
| Trifluoroacetic Acid SCHEMBL7949093 | 0.94 | CA1 (0.50) | CA1CA4FFAR3LCKFYN | |
| Trifluoroacetic Acid SCHEMBL28112665 | 0.87 | CA4 (0.38) | CA1CA4ALDH1A1TSHRCASP1 | |
| Trifluoroacetic Acid SCHEMBL28456699 | 0.84 | CA4 (0.39) | CA1CA4ALDH1A1TSHRCASP1 | |
| Trifluoroacetic Acid SCHEMBL479935 | 0.83 | FFAR3 (0.54) | CA1FFAR3LCKFYNALDH1A1 | |
| Trifluoroacetic Acid SCHEMBL29465551 | 0.83 | FFAR3 (0.54) | CA1FFAR3LCKFYNALDH1A1 | |
| Trifluoroacetic Acid SCHEMBL5242831 | 0.83 | FFAR3 (0.54) | CA1FFAR3LCKFYNALDH1A1 | |
| Trifluoroacetic Acid SCHEMBL28878905 | 0.83 | LMNA (0.46) | CA1FFAR3LCKFYNALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-117603338-A | Purifying method of semagllutide | 南京汉欣医药科技有限公司 | 2024-02-27 | — | — | CN | claimed |
| CN-115260293-B | Method for purifying ganirelix acetate | 南京汉欣医药科技有限公司 | 2023-06-06 | — | — | CN | claimed |
| CN-115260293-A | Purification method of ganirelix acetate | 南京汉欣医药科技有限公司 | 2022-11-01 | — | — | CN | claimed |
| CN-117603338-A | Purifying method of semagllutide | 南京汉欣医药科技有限公司 | 2024-02-27 | — | — | CN | disclosed |
| CN-115260293-B | Method for purifying ganirelix acetate | 南京汉欣医药科技有限公司 | 2023-06-06 | — | — | CN | disclosed |
| CN-115260293-A | Purification method of ganirelix acetate | 南京汉欣医药科技有限公司 | 2022-11-01 | — | — | CN | disclosed |
| EP-0162588-B1 | PREPARATION OF POLYMER POLYOLS | POLYOL INTERNATIONAL B.V. (NL) | 1991-10-23 | — | — | EP | disclosed |
| US-4831076-A | Preparation of polymer polyols | BP CHEMICALS LIMITED (GB) | 1989-05-16 | — | — | US | disclosed |
| EP-0162588-A1 | Preparation of polymer polyols | POLYOL INTERNATIONAL B.V. (NL) | 1985-11-27 | — | — | EP | disclosed |