Known targets — ChEMBL curated mechanism
The experimentally established mechanism targets of Trifluoroacetic Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA4 | P22748 | 4/20 | 0.38 |
| ▸ | FAHD1 | Q6P587 | 1/20 | 0.38 |
| ▸ | CASP1 | P29466 | 1/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.36 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.36 |
| ▸ | CA1 | P00915 | 1/20 | 0.35 |
| ▸ | THRB | P10828 | 1/20 | 0.35 |
| ▸ | TSHR | P16473 | 2/20 | 0.33 |
| ▸ | TP53 | P04637 | 1/20 | 0.33 |
| ▸ | CA2 | P00918 | 1/20 | 0.33 |
| ▸ | CES1 | P23141 | 1/20 | 0.32 |
| ▸ | MEN1 | O00255 | 1/20 | 0.32 |
| ▸ | LDHA | P00338 | 1/20 | 0.32 |
| ▸ | BLM | P54132 | 1/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.32 |
| ▸ | ACLY | P53396 | 2/20 | 0.31 |
| ▸ | LMNA | P02545 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Trifluoroacetic Acid SCHEMBL28456699 | 0.90 | CA4 (0.39) | CA4FAHD1CASP1ALDH1A1L3MBTL1 | |
| Trifluoroacetic Acid SCHEMBL28823737 | 0.87 | CA4 (0.38) | CA4FAHD1CASP1ALDH1A1L3MBTL1 | |
| Trifluoroacetic Acid SCHEMBL9836604 | 0.87 | CA1 (0.56) | CA4FAHD1CASP1ALDH1A1L3MBTL1 | |
| Trifluoroacetic Acid SCHEMBL3920983 | 0.86 | CA4 (0.38) | CA4FAHD1CASP1ALDH1A1L3MBTL1 | |
| Trifluoroacetic Acid SCHEMBL1853058 | 0.85 | — | — | |
| Trifluoroacetic Acid SCHEMBL30657022 | 0.84 | — | — | |
| Trifluoroacetic Acid SCHEMBL7814389 | 0.84 | ALDH1A1 (0.44) | ALDH1A1L3MBTL1CA1THRBTSHR | |
| Trifluoroacetic Acid SCHEMBL4598430 | 0.84 | — | — | |
| Trifluoroacetic Acid SCHEMBL2484766 | 0.84 | ALDH1A1 (0.44) | ALDH1A1L3MBTL1CA1THRBTSHR | |
| Trifluoroacetic Acid SCHEMBL474 | 0.84 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-118271567-A | Preparation method of hyperbranched modified poly (urethane-acrylic) resin and application of hyperbranched modified poly (urethane-acrylic) resin in cold-stamping connecting material | 江苏众立生包装科技有限公司 | 2024-07-02 | — | — | CN | claimed |
| CN-118271567-A | Preparation method of hyperbranched modified poly (urethane-acrylic) resin and application of hyperbranched modified poly (urethane-acrylic) resin in cold-stamping connecting material | 江苏众立生包装科技有限公司 | 2024-07-02 | — | — | CN | disclosed |
| CN-106279352-A | The derivant of aplysiatoxin 10 and application thereof | 上海新理念生物医药科技有限公司 | 2017-01-04 | — | — | CN | disclosed |
| CN-104487433-B | Triazolone compounds as mPGES-1 inhibitors | 格兰马克药品股份有限公司 | 2016-12-07 | — | — | CN | disclosed |