Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 2/20 | 0.46 |
| ▸ | HTR1D | P28221 | 5/20 | 0.40 |
| ▸ | GABRA1 | P14867 | 1/20 | 0.39 |
| ▸ | GABRB2 | P47870 | 1/20 | 0.39 |
| ▸ | HTR1B | P28222 | 3/20 | 0.36 |
| ▸ | TSHR | P16473 | 3/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.33 |
| ▸ | HPGD | P15428 | 2/20 | 0.33 |
| ▸ | RAB9A | P51151 | 1/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.32 |
| ▸ | NPC1 | O15118 | 1/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.32 |
| ▸ | RXRB | P28702 | 1/20 | 0.32 |
| ▸ | HTR1A | P08908 | 2/20 | 0.31 |
| ▸ | ADRA2A | P08913 | 2/20 | 0.31 |
| ▸ | ADRA2B | P18089 | 2/20 | 0.31 |
| ▸ | ADRA2C | P18825 | 2/20 | 0.31 |
| ▸ | LMNA | P02545 | 1/20 | 0.31 |
| ▸ | TP53 | P04637 | 1/20 | 0.31 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29002020 | 0.80 | POLB (0.35) | POLBHTR1DGABRA1GABRB2HTR1B | |
| SCHEMBL31697683 | 0.78 | GABRA1 (0.37) | POLBHTR1DGABRA1GABRB2TSHR | |
| SCHEMBL21350003 | 0.76 | GABRA1 (0.36) | POLBHTR1DGABRA1GABRB2 | |
| SCHEMBL11356059 | 0.76 | RAPGEF4 (0.39) | TSHRALDH1A1HPGDKMT2ALMNA | |
| SCHEMBL106587 | 0.76 | RAPGEF4 (0.39) | TSHRALDH1A1HPGDKMT2ALMNA | |
| SCHEMBL1535610 | 0.75 | POLB (0.46) | POLBHTR1DGABRA1GABRB2HTR1B | |
| Methane SCHEMBL14658320 | 0.74 | RAPGEF4 (0.38) | TSHRALDH1A1HPGDKMT2ALMNA | |
| Hydrogen Sulfide SCHEMBL29194420 | 0.74 | RAPGEF4 (0.38) | TSHRALDH1A1HPGDKMT2ALMNA | |
| SCHEMBL24336854 | 0.73 | GABRA1 (0.33) | POLBGABRA1GABRB2 | |
| SCHEMBL13631871 | 0.72 | HDAC8 (0.32) | TP53TDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4990386-A | Terpolymer of aromatic vinyl monomer, cyclohexylmaleimide, and acrylic compound | SHOWA DENKO KABUSHIKI KAISHI (JP) | 1991-02-05 | — | — | US | claimed |
| US-4990386-A | Terpolymer of aromatic vinyl monomer, cyclohexylmaleimide, and acrylic compound | SHOWA DENKO KABUSHIKI KAISHI (JP) | 1991-02-05 | — | — | US | disclosed |