SCHEMBL9836719

SCHEMBL9836719

NC(=O)NS(=O)(=O)c1cc2ccccc2s1

nearest known ligand 0.58

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CA2 P00918 2/20 0.58
HDAC1 Q13547 2/20 0.50
SLC9A1 P19634 2/20 0.48
CCR2 P41597 1/20 0.47
MALT1 Q9UDY8 1/20 0.46
TPSAB1 Q15661 1/20 0.45
HDAC3 O15379 1/20 0.45
HDAC4 P56524 1/20 0.45
HDAC7 Q8WUI4 1/20 0.45
HDAC2 Q92769 1/20 0.45
HDAC10 Q969S8 1/20 0.45
HDAC11 Q96DB2 1/20 0.45
HDAC8 Q9BY41 1/20 0.45
HDAC6 Q9UBN7 1/20 0.45
HDAC9 Q9UKV0 1/20 0.45
HDAC5 Q9UQL6 1/20 0.45
MCL1 Q07820 1/20 0.45
BCL2L1 Q07817 1/20 0.44
F10 P00742 1/20 0.42
AKR1B1 P15121 1/20 0.42

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL1575937 0.77 CA2 (0.61) CA2HDAC1SLC9A1CCR2TPSAB1
SCHEMBL16597959 0.77 CA2 (0.61) CA2HDAC1SLC9A1CCR2TPSAB1
SCHEMBL8798934 0.76 CA2 (0.51) CA2HDAC1CCR2TPSAB1HDAC3
SCHEMBL4188720 0.76 CCR2 (0.64) CA2HDAC1CCR2TPSAB1HDAC3
SCHEMBL7983231 0.76 HDAC1 (0.48) CA2HDAC1CCR2MALT1ALOX5
SCHEMBL5186163 0.74 FLT1 (0.61)
SCHEMBL329450 0.74 CA2 (0.67) CA2HDAC1SLC9A1CCR2HDAC3
SCHEMBL792780 0.74 CA2 (1.00) CA2CA1CA9
SCHEMBL16756206 0.74 HDAC1 (0.62) CA2HDAC1CCR2TPSAB1MCL1
SCHEMBL329294 0.74 CA2 (0.71) CA2HDAC1SLC9A1CCR2TPSAB1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 13 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0146263-B1 HERBICIDAL SUBSTITUTED-THIOPHENE, FURAN AND PYRROLE SULFONAMIDES E.I. DU PONT DE NEMOURS AND COMPANY (US) 1991-05-15 EP disclosed
EP-0368897-A1 HERBICIDAL SULFONAMIDES E.I. DU PONT DE NEMOURS AND COMPANY (US) 1990-05-23 EP disclosed
US-4921527-A Herbicidal sulfonamides E. I. DU PONT DE NEMOURS AND COMPANY (US) 1990-05-01 US disclosed
US-4846874-A PRE- AND POSTEMERGENCE HERBICIDES; PLANT GROWTH REGULATORS E. I. DU PONT DE NEMOURS AND COMPANY (US) 1989-07-11 US disclosed
US-4844727-A HETEROCYCLIC E. I. DU PONT DE NEMOURS AND COMPANY (US) 1989-07-04 US disclosed
WO-1989000994-A2 HERBICIDAL SULFONAMIDES E.I. DU PONT DE NEMOURS AND COMPANY (US) 1989-02-09 WO disclosed
EP-0301919-A2 Herbicidal sulfonamides E.I. DU PONT DE NEMOURS AND COMPANY (US) 1989-02-01 EP disclosed
US-4737184-A PLANT GROWTH REGULATORS E. I. DU PONT DE NEMOURS AND COMPANY (US) 1988-04-12 US disclosed
US-4720298-A PLANT GROWTH REGULATORS, PREEMERGENCE OR POSTEMERGENCE HERBICIDES E. I. DU PONT DE NEMOURS AND COMPANY (US) 1988-01-19 US disclosed
US-4582527-A HERBICIDES, PLANT GROWTH REGULATOR E. I. DU PONT DE NEMOURS AND COMPANY (US) 1986-04-15 US disclosed
EP-0146263-A1 Herbicidal substituted-thiophene, furan and pyrrole sulfonamides E.I. DU PONT DE NEMOURS AND COMPANY (US) 1985-06-26 EP disclosed
US-4492596-A HERBICIDES E. I. DU PONT DE NEMOURS AND COMPANY (US) 1985-01-08 US disclosed
EP-0079683-A2 Herbicidal sulfonamides E.I. DU PONT DE NEMOURS AND COMPANY (US) 1983-05-25 EP disclosed