Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EGFR | P00533 | 2/20 | 0.36 |
| ▸ | RPS6KB1 | P23443 | 5/20 | 0.35 |
| ▸ | CRHR1 | P34998 | 2/20 | 0.34 |
| ▸ | AKT1 | P31749 | 2/20 | 0.33 |
| ▸ | ACACB | O00763 | 1/20 | 0.33 |
| ▸ | AURKA | O14965 | 3/20 | 0.32 |
| ▸ | SCN1A | P35498 | 3/20 | 0.32 |
| ▸ | SCN5A | Q14524 | 3/20 | 0.32 |
| ▸ | SCN8A | Q9UQD0 | 3/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9193841 | 0.82 | CRHR1 (0.39) | EGFRRPS6KB1CRHR1AKT1 | |
| SCHEMBL9523756 | 0.82 | CRHR1 (0.39) | EGFRRPS6KB1CRHR1AKT1ACACB | |
| SCHEMBL9526898 | 0.81 | RPS6KB1 (0.39) | EGFRRPS6KB1AKT1ACACBAURKA | |
| SCHEMBL9084666 | 0.81 | PTGER4 (0.40) | EGFRRPS6KB1CRHR1AURKA | |
| SCHEMBL9216328 | 0.81 | AURKA (0.42) | EGFRRPS6KB1CRHR1AKT1AURKA | |
| SCHEMBL9869337 | 0.80 | TDP1 (0.38) | EGFRCRHR1ACACB | |
| SCHEMBL9775791 | 0.80 | EGFR (0.36) | EGFRRPS6KB1CRHR1AKT1ACACB | |
| SCHEMBL9524682 | 0.80 | EGFR (0.36) | EGFRRPS6KB1CRHR1ACACB | |
| SCHEMBL9215501 | 0.80 | EGFR (0.36) | EGFRRPS6KB1CRHR1AKT1AURKA | |
| SCHEMBL9523823 | 0.80 | CRHR1 (0.42) | EGFRRPS6KB1CRHR1AKT1AURKA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0424125-A2 | Aralkylamine derivatives, preparation method thereof and fungicides containing the same | UBE INDUSTRIES, LTD. (JP) | 1991-04-24 | — | — | EP | disclosed |