Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EGFR | P00533 | 2/20 | 0.36 |
| ▸ | RPS6KB1 | P23443 | 2/20 | 0.36 |
| ▸ | AURKA | O14965 | 1/20 | 0.36 |
| ▸ | PDPK1 | O15530 | 1/20 | 0.36 |
| ▸ | AKT1 | P31749 | 3/20 | 0.35 |
| ▸ | CRHR1 | P34998 | 2/20 | 0.34 |
| ▸ | PDE2A | O00408 | 5/20 | 0.32 |
| ▸ | PDE3A | Q14432 | 1/20 | 0.32 |
| ▸ | PDE10A | Q9Y233 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9216328 | 0.92 | AURKA (0.42) | EGFRRPS6KB1AURKAPDPK1AKT1 | |
| SCHEMBL9523428 | 0.90 | EGFR (0.36) | EGFRRPS6KB1AURKAPDPK1AKT1 | |
| SCHEMBL9524057 | 0.86 | EGFR (0.36) | EGFRRPS6KB1AURKAPDPK1AKT1 | |
| SCHEMBL9193841 | 0.84 | CRHR1 (0.39) | EGFRRPS6KB1AKT1CRHR1 | |
| SCHEMBL9084666 | 0.83 | PTGER4 (0.40) | EGFRRPS6KB1AURKACRHR1 | |
| Hydrochloric Acid SCHEMBL9523871 | 0.82 | PTGER4 (0.39) | EGFRRPS6KB1AURKACRHR1 | |
| SCHEMBL9523756 | 0.82 | CRHR1 (0.39) | EGFRRPS6KB1AURKAAKT1CRHR1 | |
| SCHEMBL9212072 | 0.81 | EGFR (0.36) | EGFRRPS6KB1AKT1CRHR1 | |
| SCHEMBL8303141 | 0.81 | EGFR (0.38) | EGFRRPS6KB1AKT1CRHR1 | |
| SCHEMBL9212840 | 0.81 | ALDH1A1 (0.35) | EGFRRPS6KB1AURKAPDPK1AKT1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5141941-A | ARALKYLAMINE DERIVATIVES, AND FUNGICIDES CONTAINING THE SAME | UBE INDUSTRIES, LTD. (JP) | 1992-08-25 | — | — | US | claimed |
| EP-0370704-B1 | Aralkylamine derivatives, preparation thereof and fungicides containing the same | UBE INDUSTRIES (JP) | 1995-02-01 | — | — | EP | disclosed |
| US-5141941-A | ARALKYLAMINE DERIVATIVES, AND FUNGICIDES CONTAINING THE SAME | UBE INDUSTRIES, LTD. (JP) | 1992-08-25 | — | — | US | disclosed |
| EP-0370704-A2 | Aralkylamine derivatives, preparation thereof and fungicides containing the same | UBE INDUSTRIES, LTD. (JP) | 1990-05-30 | — | — | EP | disclosed |