SCHEMBL9836882

SCHEMBL9836882

C=C(C)C(OC(=O)Nc1cc(Cl)ccc1Cl)C(=O)OC

nearest known ligand 0.46

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
EPHX1 P07099 1/20 0.46
MEN1 O00255 5/20 0.46
KMT2A Q03164 5/20 0.46
POLB P06746 1/20 0.46
CASP3 P42574 1/20 0.43
GAA P10253 2/20 0.42
MAPT P10636 2/20 0.42
LMNA P02545 2/20 0.41
HTT P42858 2/20 0.41
MAPK1 P28482 1/20 0.41
L3MBTL1 Q9Y468 1/20 0.41
PDK1 Q15118 1/20 0.41
PDK2 Q15119 1/20 0.41
PDK3 Q15120 1/20 0.41
PDK4 Q16654 1/20 0.41
ALDH1A1 P00352 5/20 0.41
HPGD P15428 1/20 0.41
TSHR P16473 1/20 0.41
SMN1; SMN2 Q16637 1/20 0.41
HSD17B10 Q99714 1/20 0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9834529 0.90 USP2 (0.50) MEN1KMT2APOLBCASP3GAA
SCHEMBL9836328 0.88 TDP1 (0.44) MEN1KMT2AMAPTLMNAHTT
SCHEMBL9867843 0.85 MEN1 (0.41) MEN1KMT2APOLBCASP3GAA
SCHEMBL9837102 0.84 KMT2A (0.49) MEN1KMT2AGAAMAPTLMNA
SCHEMBL9835398 0.84 SMN1; SMN2 (0.49) MEN1KMT2APOLBCASP3LMNA
SCHEMBL9835786 0.81 HPGD (0.43) MEN1KMT2APOLBGAAMAPT
SCHEMBL9836424 0.81 MAPT (0.52) EPHX1MEN1KMT2APOLBGAA
SCHEMBL9837587 0.81 LMNA (0.47) MEN1KMT2APOLBGAAMAPT
SCHEMBL9837038 0.81 HTT (0.50) EPHX1MEN1KMT2AMAPTLMNA
SCHEMBL9836182 0.80 ALDH1A1 (0.39) MEN1KMT2APOLBMAPTLMNA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0241559-B1 OXAZOLIDINEDIONE DERIVATIVES, PROCESS FOR THEIR PREPARATION, AND HERBICIDES CONTAINING THE SAME SAGAMI CHEMICAL RESEARCH CENTER (JP) 1991-10-30 EP disclosed
US-4983751-A Chemical intermediates SAGAMI CHEMICAL RESEARCH CENTER (JP) 1991-01-08 US disclosed
US-4818272-A NONPHYTOTOXICITY FOR CROPS HELICAL STREAMS SAGAMI CHEMICAL RESEARCH CENTER (JP) 1989-04-04 US disclosed
EP-0241559-A1 OXAZOLIDINEDIONE DERIVATIVES, PROCESS FOR THEIR PREPARATION, AND HERBICIDES CONTAINING THE SAME SAGAMI CHEMICAL RESEARCH CENTER (JP) 1987-10-21 EP disclosed