Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PARP1 | P09874 | 12/20 | 0.97 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.37 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.37 |
| ▸ | HPGD | P15428 | 2/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
| ▸ | HTT | P42858 | 1/20 | 0.33 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.33 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.33 |
| ▸ | POLB | P06746 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4761629 | 0.98 | PARP1 (1.00) | PARP1SMN1; SMN2ALOX15HPGDKDM4E | |
| SCHEMBL5522439 | 0.95 | PARP1 (1.00) | PARP1SMN1; SMN2ALOX15HPGDKDM4E | |
| SCHEMBL9836295 | 0.81 | PARP1 (0.69) | PARP1 | |
| SCHEMBL5527862 | 0.80 | PARP1 (0.68) | PARP1 | |
| SCHEMBL4724551 | 0.80 | PARP1 (0.63) | PARP1SMN1; SMN2ALOX15HPGDPOLB | |
| SCHEMBL5525103 | 0.79 | PARP1 (0.67) | PARP1SMN1; SMN2ALOX15HPGDKDM4E | |
| SCHEMBL5532024 | 0.78 | PARP1 (0.65) | PARP1SMN1; SMN2ALOX15HPGDPOLB | |
| SCHEMBL4763087 | 0.76 | PARP1 (0.63) | PARP1 | |
| SCHEMBL4724958 | 0.76 | PARP1 (0.63) | PARP1KDM4EALDH1A1HIF1A | |
| SCHEMBL5534195 | 0.76 | PARP1 (0.62) | PARP1SMN1; SMN2ALOX15HPGDKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0104522-B1 | NEW PYRAZOLO(3,4-B)PYRIDINE DERIVATIVES AND PROCESS FOR PRODUCING THEM | GRUPPO LEPETIT S.p.A. (IT) | 1991-05-29 | — | — | EP | disclosed |