SCHEMBL9836995

SCHEMBL9836995

CC(C)=C1OC(=O)N(c2ccc(Cl)cc2Cl)C1=O

nearest known ligand 0.53

Predicted protein targets (top 17)

geneUniProtsupporting neighboursconfidence
BCL2A1 Q16548 1/20 0.42
MEN1 O00255 1/20 0.41
MAPT P10636 1/20 0.41
ALOX12 P18054 1/20 0.41
KMT2A Q03164 1/20 0.41
ALDH1A1 P00352 4/20 0.40
LMNA P02545 1/20 0.38
GRM1 Q13255 3/20 0.37
GRM4 Q14833 3/20 0.37
NOTUM Q6P988 2/20 0.37
SMN1; SMN2 Q16637 2/20 0.37
G6PD P11413 1/20 0.37
TLR8 Q9NR97 1/20 0.36
AKR1C3 P42330 1/20 0.36
OPRM1 P35372 1/20 0.36
CNR2 P34972 1/20 0.36
HPGD P15428 1/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9837002 0.86 BCL2A1 (0.39) BCL2A1MEN1MAPTALOX12KMT2A
SCHEMBL8888450 0.86 MEN1 (0.40) BCL2A1MEN1MAPTALOX12KMT2A
SCHEMBL9835672 0.85 ALDH1A1 (0.42) BCL2A1MEN1MAPTALOX12KMT2A
SCHEMBL9835991 0.76 TSHR (0.39) BCL2A1MAPTALDH1A1SMN1; SMN2HPGD
SCHEMBL7932830 0.73 PPOX (0.32) MEN1MAPTALOX12KMT2AHPGD
SCHEMBL9837006 0.71 BCL2A1 (0.38) BCL2A1MEN1MAPTALOX12KMT2A
SCHEMBL9835675 0.70 BCL2A1 (0.37) BCL2A1MEN1MAPTALOX12KMT2A
SCHEMBL7934621 0.67 ELANE (0.47) MEN1MAPTALOX12KMT2AALDH1A1
SCHEMBL9837248 0.67 HPGD (0.30) HPGD
SCHEMBL8886667 0.67 ELANE (0.41) MEN1MAPTALOX12KMT2AALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0241559-B1 OXAZOLIDINEDIONE DERIVATIVES, PROCESS FOR THEIR PREPARATION, AND HERBICIDES CONTAINING THE SAME SAGAMI CHEMICAL RESEARCH CENTER (JP) 1991-10-30 EP disclosed
US-4983751-A Chemical intermediates SAGAMI CHEMICAL RESEARCH CENTER (JP) 1991-01-08 US disclosed
US-4818272-A NONPHYTOTOXICITY FOR CROPS HELICAL STREAMS SAGAMI CHEMICAL RESEARCH CENTER (JP) 1989-04-04 US disclosed
EP-0241559-A1 OXAZOLIDINEDIONE DERIVATIVES, PROCESS FOR THEIR PREPARATION, AND HERBICIDES CONTAINING THE SAME SAGAMI CHEMICAL RESEARCH CENTER (JP) 1987-10-21 EP disclosed