SCHEMBL9837166

SCHEMBL9837166

COC(=O)CON1C(=O)C(C)=C(C)C1=O

nearest known ligand 0.64

Predicted protein targets (top 17)

geneUniProtsupporting neighboursconfidence
KMT2A Q03164 1/20 0.37
TSHR P16473 4/20 0.36
ALDH1A1 P00352 4/20 0.36
KDM4E B2RXH2 3/20 0.36
SMN1; SMN2 Q16637 2/20 0.36
HSD17B10 Q99714 2/20 0.36
CYP1A2 P05177 1/20 0.35
CYP2C9 P11712 1/20 0.35
PKM P14618 1/20 0.34
LMNA P02545 1/20 0.33
MGAM O43451 1/20 0.33
GAA P10253 1/20 0.33
SI P14410 1/20 0.33
MGAM2 Q2M2H8 1/20 0.33
GLA P06280 1/20 0.33
POLB P06746 1/20 0.33
TP53 P04637 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9315522 0.79 ALDH1A1 (0.45) KMT2ATSHRALDH1A1KDM4ECYP1A2
SCHEMBL1562501 0.78 ALDH1A1 (0.61) KMT2AALDH1A1SMN1; SMN2CYP1A2CYP2C9
SCHEMBL22152246 0.71 CASP3 (0.48) KMT2AALDH1A1KDM4ESMN1; SMN2HSD17B10
SCHEMBL5419285 0.65 ALDH1A1 (0.58) KMT2ATSHRALDH1A1KDM4EHSD17B10
SCHEMBL9314835 0.64 TSHR (0.36) TSHRALDH1A1KDM4EHSD17B10LMNA
SCHEMBL1335833 0.62 TSHR (0.56) KMT2ATSHRALDH1A1KDM4EHSD17B10
SCHEMBL29374 0.62
SCHEMBL10872888 0.61 ALDH1A1 (0.34) ALDH1A1PKM
SCHEMBL29186436 0.60
SCHEMBL21409742 0.60

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
JP-3169857-A None JP disclosed
JP-H03169857-A IMIDE COMPOUND, ITS ACID ADDITION SALT, PRODUCTION THEREOF AND PLANT GROWTH REGULATOR CONTAINING THE SAME AS ACTIVE INGREDIENT SUMITOMO CHEM CO LTD 1991-07-23 JP disclosed