Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP1A2 | P05177 | 1/20 | 0.51 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.51 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.51 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.51 |
| ▸ | HPGD | P15428 | 1/20 | 0.51 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.51 |
| ▸ | MEN1 | O00255 | 2/20 | 0.50 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.50 |
| ▸ | CXCR4 | P61073 | 1/20 | 0.50 |
| ▸ | MAPK10 | P53779 | 1/20 | 0.50 |
| ▸ | GFER | P55789 | 1/20 | 0.50 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.48 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.48 |
| ▸ | RAB9A | P51151 | 3/20 | 0.48 |
| ▸ | GRM5 | P41594 | 1/20 | 0.47 |
| ▸ | NPC1 | O15118 | 1/20 | 0.47 |
| ▸ | LMNA | P02545 | 1/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.47 |
| ▸ | MAPKAPK2 | P49137 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12125849 | 0.84 | RIOK2 (0.51) | CYP1A2MEN1KMT2ACXCR4MAPK10 | |
| SCHEMBL5025515 | 0.82 | MEN1 (0.50) | MEN1KMT2ACXCR4MAPK10GFER | |
| SCHEMBL154709 | 0.81 | CXCR4 (0.49) | MEN1KMT2ACXCR4MAPK10GFER | |
| SCHEMBL904444 | 0.79 | NPC1 (0.60) | HPGDMEN1KMT2AMAPK10GFER | |
| SCHEMBL29408382 | 0.79 | NPC1 (0.60) | HPGDMEN1KMT2AMAPK10GFER | |
| SCHEMBL7531008 | 0.79 | RAB9A (0.56) | CYP1A2CYP3A4CYP2D6CYP2C9HPGD | |
| SCHEMBL25201789 | 0.79 | CXCR4 (0.56) | MEN1KMT2ACXCR4MAPK10GFER | |
| SCHEMBL14030994 | 0.79 | MEN1 (0.43) | MEN1KMT2ACXCR4MAPK10GFER | |
| SCHEMBL31390266 | 0.79 | MEN1 (0.59) | MEN1KMT2AMAPK10GFERSMN1; SMN2 | |
| SCHEMBL29582475 | 0.78 | MEN1 (0.64) | MEN1KMT2AMAPK10GFERSMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5028603-A | Platelet-Activating Factor Antagonist; Useful In Treatment Of Inflammatory Diseases, Allergic Diseases, Asthma, Respiratory System Disorders | YOSHITOMI PHARMACEUTICAL INDUSTRIES, LTD. (JP) | 1991-07-02 | — | — | US | disclosed |
| EP-0316456-A1 | ESTER-SUBSTITUTED THIENOTRIAZOLODIAZEPINE COMPOUNDS AND THEIR MEDICINAL USE | Yoshitomi Pharmaceutical Industries, Ltd. (JP) | 1989-05-24 | — | — | EP | disclosed |