Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RAB9A | P51151 | 9/20 | 0.56 |
| ▸ | NPC1 | O15118 | 6/20 | 0.56 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.55 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.55 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.55 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.55 |
| ▸ | HPGD | P15428 | 1/20 | 0.55 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.55 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.45 |
| ▸ | MEN1 | O00255 | 2/20 | 0.45 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.45 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.45 |
| ▸ | MAPKAPK2 | P49137 | 1/20 | 0.44 |
| ▸ | CXCR4 | P61073 | 1/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.44 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.43 |
| ▸ | LMNA | P02545 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4926432 | 0.80 | ADRB2 (0.52) | — | |
| SCHEMBL7460307 | 0.80 | SYK (0.55) | — | |
| SCHEMBL9837237 | 0.79 | CYP1A2 (0.51) | RAB9ANPC1CYP1A2CYP3A4CYP2D6 | |
| SCHEMBL14368037 | 0.79 | GRM4 (0.56) | PTGS1PTGS2SMN1; SMN2 | |
| SCHEMBL13185630 | 0.78 | IKBKB (0.60) | RAB9ANPC1KMT2AMEN1MAPKAPK2 | |
| SCHEMBL49571 | 0.78 | RAB9A (0.55) | RAB9ANPC1CYP1A2CYP3A4CYP2D6 | |
| SCHEMBL16432125 | 0.78 | HPGD (0.61) | RAB9ANPC1CYP1A2CYP3A4CYP2D6 | |
| SCHEMBL27028583 | 0.77 | SYK (0.69) | RAB9ANPC1HPGDALDH1A1KMT2A | |
| SCHEMBL3786298 | 0.77 | HPGD (0.54) | RAB9ANPC1HPGDALDH1A1SMN1; SMN2 | |
| SCHEMBL15331048 | 0.77 | NPC1 (0.49) | RAB9ANPC1CYP1A2CYP3A4CYP2D6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4308117-A1 | METHODS AND COMPOSITIONS FOR TREATING CONDITIONS ASSOCIATED WITH HYPERMINERALIZATION | Université de Lausanne (CH) | 2024-01-24 | — | — | EP | disclosed |
| WO-2022194953-A1 | METHODS AND COMPOSITIONS FOR TREATING CONDITIONS ASSOCIATED WITH HYPERMINERALIZATION | Université de Lausanne (CH) | 2022-09-22 | — | — | WO | disclosed |
| EP-0233461-B2 | 4,5,6-Substituted-2-pyrimidinamines | AMERICAN CYANAMID CO (US) | 2002-05-29 | — | — | EP | disclosed |