Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DPP4 | P27487 | 6/20 | 0.60 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.57 |
| ▸ | DRD1 | P21728 | 1/20 | 0.57 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.53 |
| ▸ | LMNA | P02545 | 2/20 | 0.53 |
| ▸ | ABCC4 | O15439 | 1/20 | 0.53 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.53 |
| ▸ | TOP2A | P11388 | 4/20 | 0.50 |
| ▸ | TOP2B | Q02880 | 4/20 | 0.50 |
| ▸ | DHFR | P00374 | 1/20 | 0.46 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.46 |
| ▸ | ATP6V1B2 | P21281 | 1/20 | 0.46 |
| ▸ | TBXA2R | P21731 | 1/20 | 0.46 |
| ▸ | EDNRA | P25101 | 1/20 | 0.46 |
| ▸ | TARBP2 | Q15633 | 1/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9837301 | 0.87 | LMNA (0.62) | DPP4CHRM2DRD1KDM4ELMNA | |
| SCHEMBL9669861 | 0.85 | DPP4 (0.68) | DPP4CHRM2DRD1KDM4ELMNA | |
| SCHEMBL10377610 | 0.85 | DPP4 (0.62) | DPP4CHRM2DRD1KDM4ELMNA | |
| SCHEMBL9837344 | 0.85 | DPP4 (0.62) | DPP4CHRM2DRD1KDM4ELMNA | |
| SCHEMBL9838732 | 0.85 | DPP4 (0.62) | DPP4CHRM2DRD1KDM4ELMNA | |
| SCHEMBL9838624 | 0.85 | DPP4 (0.62) | DPP4CHRM2DRD1KDM4ELMNA | |
| SCHEMBL9865696 | 0.85 | DPP4 (0.55) | DPP4CHRM2DRD1KDM4ELMNA | |
| Hydrochloric Acid SCHEMBL10551866 | 0.84 | DPP4 (0.61) | DPP4CHRM2DRD1KDM4ELMNA | |
| SCHEMBL9522848 | 0.84 | DPP4 (0.67) | DPP4CHRM2DRD1KDM4ELMNA | |
| Hydrochloric Acid SCHEMBL10549780 | 0.84 | DPP4 (0.59) | DPP4CHRM2DRD1KDM4ELMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0159174-B1 | SUBSTITUTED NAPHTHYRIDINE-, QUINOLINE- AND BENZOXAZINE- CARBOXYLIC ACIDS AS ANTIBACTERIAL AGENTS AND PROCESSES FOR THEIR PRODUCTION | WARNER-LAMBERT COMPANY (US) | 1991-10-23 | — | — | EP | disclosed |