Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 6/20 | 0.62 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.62 |
| ▸ | ATP6V1B2 | P21281 | 1/20 | 0.62 |
| ▸ | TBXA2R | P21731 | 1/20 | 0.62 |
| ▸ | EDNRA | P25101 | 1/20 | 0.62 |
| ▸ | TARBP2 | Q15633 | 1/20 | 0.62 |
| ▸ | DRD3 | P35462 | 1/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.47 |
| ▸ | MEN1 | O00255 | 2/20 | 0.47 |
| ▸ | ABCC4 | O15439 | 2/20 | 0.47 |
| ▸ | PKM | P14618 | 1/20 | 0.47 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.47 |
| ▸ | DPP4 | P27487 | 6/20 | 0.47 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.47 |
| ▸ | DRD1 | P21728 | 1/20 | 0.47 |
| ▸ | CASP1 | P29466 | 1/20 | 0.45 |
| ▸ | KDM4E | B2RXH2 | 6/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.44 |
| ▸ | HPGD | P15428 | 5/20 | 0.44 |
| ▸ | NPC1 | O15118 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9838598 | 0.87 | LMNA (0.61) | LMNACYP2C9ATP6V1B2TBXA2REDNRA | |
| SCHEMBL9837590 | 0.87 | LMNA (0.61) | LMNACYP2C9ATP6V1B2TBXA2REDNRA | |
| SCHEMBL9837356 | 0.87 | DPP4 (0.60) | LMNACYP2C9ATP6V1B2TBXA2REDNRA | |
| SCHEMBL9838649 | 0.87 | LMNA (0.60) | LMNACYP2C9ATP6V1B2TBXA2REDNRA | |
| Hydrochloric Acid SCHEMBL9837293 | 0.86 | LMNA (0.59) | LMNACYP2C9ATP6V1B2TBXA2REDNRA | |
| SCHEMBL10675814 | 0.85 | LMNA (0.69) | LMNACYP2C9ATP6V1B2TBXA2REDNRA | |
| SCHEMBL9837577 | 0.84 | LMNA (0.58) | LMNACYP2C9ATP6V1B2TBXA2REDNRA | |
| SCHEMBL9837392 | 0.83 | LMNA (0.61) | LMNACYP2C9ATP6V1B2TBXA2REDNRA | |
| SCHEMBL9837624 | 0.82 | LMNA (0.62) | LMNACYP2C9ATP6V1B2TBXA2REDNRA | |
| SCHEMBL4904141 | 0.82 | LMNA (0.79) | LMNACYP2C9ATP6V1B2TBXA2REDNRA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0159174-B1 | SUBSTITUTED NAPHTHYRIDINE-, QUINOLINE- AND BENZOXAZINE- CARBOXYLIC ACIDS AS ANTIBACTERIAL AGENTS AND PROCESSES FOR THEIR PRODUCTION | WARNER-LAMBERT COMPANY (US) | 1991-10-23 | — | — | EP | disclosed |