SCHEMBL9837472

SCHEMBL9837472

C=C(CCCC)C(OC(=O)Nc1ccc(Cl)cc1)C(=O)OC

nearest known ligand 0.48

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MAPT P10636 3/20 0.48
NPC1 O15118 5/20 0.44
RAB9A P51151 5/20 0.44
SMN1; SMN2 Q16637 5/20 0.44
L3MBTL1 Q9Y468 3/20 0.44
HPGD P15428 3/20 0.44
ALDH1A1 P00352 3/20 0.43
KMT2A Q03164 2/20 0.43
CASP1 P29466 1/20 0.41
LMNA P02545 1/20 0.41
UTS2R Q9UKP6 1/20 0.41
ATM Q13315 1/20 0.40
CCKBR P32239 1/20 0.39
CYP1A2 P05177 1/20 0.39
CYP2C9 P11712 1/20 0.39
CYP2C19 P33261 1/20 0.39
KDM4E B2RXH2 1/20 0.39
MAPK1 P28482 1/20 0.39
MCL1 Q07820 1/20 0.39
CHRM2 P08172 1/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9835915 0.95 MAPT (0.46) MAPTNPC1RAB9ASMN1; SMN2L3MBTL1
SCHEMBL27318233 0.89 MAPT (0.46) MAPTNPC1RAB9ASMN1; SMN2L3MBTL1
SCHEMBL9835172 0.88 MAPT (0.52) MAPTNPC1RAB9ASMN1; SMN2L3MBTL1
SCHEMBL27314996 0.85 MAPT (0.44) MAPTNPC1RAB9ASMN1; SMN2L3MBTL1
SCHEMBL9836424 0.81 MAPT (0.52) MAPTNPC1RAB9ASMN1; SMN2L3MBTL1
SCHEMBL9867583 0.78 RORC (0.39) MAPTNPC1RAB9ASMN1; SMN2L3MBTL1
SCHEMBL9834808 0.77 MAPT (0.54) MAPTNPC1RAB9ASMN1; SMN2L3MBTL1
SCHEMBL9835741 0.76 MAPT (0.48) MAPTNPC1RAB9ASMN1; SMN2L3MBTL1
SCHEMBL9835438 0.76 MAPT (0.48) MAPTNPC1RAB9ASMN1; SMN2L3MBTL1
SCHEMBL9834379 0.76 MAPT (0.52) MAPTRAB9ASMN1; SMN2L3MBTL1HPGD

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-1059718-A The weedicide that contains the  oxazolidinedione derivatives SAGAMI CHEM RES (JP) 1992-03-25 CN disclosed
EP-0241559-B1 OXAZOLIDINEDIONE DERIVATIVES, PROCESS FOR THEIR PREPARATION, AND HERBICIDES CONTAINING THE SAME SAGAMI CHEMICAL RESEARCH CENTER (JP) 1991-10-30 EP disclosed
US-4983751-A Chemical intermediates SAGAMI CHEMICAL RESEARCH CENTER (JP) 1991-01-08 US disclosed
US-4818272-A NONPHYTOTOXICITY FOR CROPS HELICAL STREAMS SAGAMI CHEMICAL RESEARCH CENTER (JP) 1989-04-04 US disclosed
EP-0241559-A1 OXAZOLIDINEDIONE DERIVATIVES, PROCESS FOR THEIR PREPARATION, AND HERBICIDES CONTAINING THE SAME SAGAMI CHEMICAL RESEARCH CENTER (JP) 1987-10-21 EP disclosed